胎儿胼胝体缺如产前超声及磁共振诊断的应用分析  

The role of prenatal ultrasound and MRI in diagnosis of fetal agenesis of corpus callosum

作　　者：兰为顺[1] 夏薇[1] 刘芳[1] 余旭东[1] 袁先宏[1] 李琳[1] 苏永学 杨文忠[1] 陈欣林[2] 杨小红[2] 

机构地区：[1]湖北省妇幼保健院医学影像科,武汉430070 [2]湖北省妇幼保健院超声影像科,武汉430070

出　　处：《中华医学超声杂志（电子版）》2015年第5期374-378,共5页Chinese Journal of Medical Ultrasound(Electronic Edition)

摘　　要：目的分析胎儿胼胝体缺如的产前超声及磁共振诊断价值。方法对2013年7月至2014年12月湖北省妇幼保健院产前超声筛查怀疑胼胝体缺如的67例胎儿于超声检查后3 d内行颅脑磁共振检查,与引产或出生后检查结果对照,对产前超声及磁共振检查结果进行分析。结果产前超声怀疑胼胝体缺如的67例胎儿磁共振检查后均证实为胼胝体缺如,其中胼胝体完全缺如58例,胼胝体部分缺如9例(均为胼胝体体部和压部缺如)。胎儿胼胝体缺如在磁共振正中矢状位图像上表现为胼胝体完全或部分缺如,脑回呈放射状排列;在横轴位和冠状位图像上表现为侧脑室轻至中度扩张,形态失常。结论磁共振对胎儿胼胝体缺如有较高的诊断价值,可作为产前超声的补充和验证方法,在产前超声检查怀疑胎儿胼胝体异常时,应行胎儿磁共振检查明确诊断。超声与磁共振联合筛查,是胎儿中枢神经系统畸形产前检查中重要的影像学诊断方法。Objective To discuss the value of prenatal ultrasound and MRI in diagnosis of fetal agenesis of corpus callosum （ACC）. Methods Sixty-seven fetuses from Hubei Maternal and Children＇s Hospital performed fetal MR/from July 2013 to December 2014 were included in this study. All fetuses （67 cases） with suspected ACC were studied with a 1.5T MR unit within 3 days after ultrasound examination. Prenatal ultrasound and MRI findings were studied. Results All the 67 ACCs previously suspected on ultrasound were confirmed by MRI. Among the 67 ACCs, 58 cases were complete ACC and 9 cases were partial ACC. Corpus callosum body and/or splenium absence was found in all 9 partial ACC cases. In all cases, on MRI, corpus callosum complete or partial absence was showed on the median sagittal images, and mild to moderate ventriculomegaly and abnormal morphology in lateral ventricle was shown on the axial or coronary images. Conclusions MRI has high value in diagnosis of ACC. When ACC is found or suspected by ultrasonophy, MRI examination is suggested to confirm the diagnosis.

关 键 词：超声检查 产前 磁共振成像 胎儿 胼胝体缺如 

分 类 号：R445[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]