口腔精准医学:现状与挑战  

Precision stomatology: current status and challenges

作　　者：徐欣[1] 郑欣[1] 郑黎薇[1] 程磊[1] 周学东[1] 

机构地区：[1]口腔疾病研究国家重点实验室华西口腔医院(四川大学),成都610041

出　　处：《华西口腔医学杂志》2015年第3期315-321,共7页West China Journal of Stomatology

基　　金：国家自然科学基金资助项目(81170959;81200782;81-430011);"十二五"国家科技支撑计划基金资助项目(2012BAI-07B03)

摘　　要：精准医学是人类基因组计划的延续,是医学发展的必然产物,是一种考虑人群基因、环境及生活方式个体差异的促进健康和治疗疾病的新兴医学模式。本文首次提出口腔精准医学的概念,以口腔典型疾病为例,结合近期的研究成果与学者观点,阐述口腔精准医学对口腔学科发展的指导意义及实现口腔精准医学将面对的机遇与挑战。The completion of human genome project and the progress in medical practice have inevitably lead to the deve-lopment of precision medicine, which is a medical model that proposes the customization of medical care including medical decisions, practices, and/or medical products with patient’s genetic background, environmental factors and life behavior being taken into account. The current work proposed precision stomatology for the first time, and by integrating data reported in recent literature, we described the current practice of precision stomatology in multiple disciplines in modern dentistry. The clinical significance of precision stomatology and its future challenges have also been discussed.

关 键 词：精准医学 口腔精准医学 个体化医疗 生物样本库 

分 类 号：R78[医药卫生—口腔医学]