丹参多酚酸对急性脑梗死患者运动和认知功能影响的临床研究  

Clinical study on the effect of salvianolate on motor and cognitive function of patients with acute cerebral infarction

作　　者：张凤[1] 邱菊[1] 张黎明[1] 黄永璐[1] 高宗良[1] 

机构地区：[1]安徽医科大学第二附属医院神经内科,合肥230601

出　　处：《中国临床保健杂志》2015年第3期232-234,共3页Chinese Journal of Clinical Healthcare

基　　金：国家自然科学基金(81000534)

摘　　要：目的研究丹参多酚酸对急性脑梗死患者运动和认知功能恢复的作用。方法按随机数字表法将研究对象分为常规治疗组和研究组,运用相关量表分别于治疗前后对两组患者行运动和认知功能评定,并对两组患者行安全性评定。结果治疗前两组间各评分比较差异均无统计学意义;治疗后两组间美国国立卫生研究院卒中量表、日常生活活动能力、蒙特利尔认知评估、简易精神状态检查量表评分差异有统计学意义(P<0.05),残疾程度组间比较差异无统计学意义(P>0.05)。结论丹参多酚酸可促进急性脑梗死患者认知功能的恢复。Objective To understand the effect of salvianolate on motor and cognitive function of patients-with acute cerebral infarction by a prospective controlled study.Methods The subjects were divided into control group and experimental group,and the motor and cognitive functions of the two groups were accessed before and after treatment used relevant scales,and the safety of the two groups were also evaluated.Results No significant differ-ence in the various scale scores was found between two groups before treatment.NIHSS,BI,MOCA and MMSE scores of the two groups showed significant differences after treatment（P 〈0.05）,but mRS showed no significant difference between two groups （P 〉0.05）.Conclusion Salvianolate can promote recovery of the cognitive function of patients with acute cerebral infarction.

关 键 词：脑梗死 运动障碍 认知障碍 丹参 

分 类 号：R743.33[医药卫生—神经病学与精神病学]