住院白血病患者生命质量与焦虑抑郁的相关性研究  

The correlation of quality of life with anxiety and depression in patients with leukemia

作　　者：丁宁[1] 陶治荣[1] 胡芳[1] 

机构地区：[1]蚌埠医学院第一附属医院血液科,安徽蚌埠233004

出　　处：《蚌埠医学院学报》2015年第5期672-675,共4页Journal of Bengbu Medical College

基　　金：蚌埠医学院自然科学研究资助项目(Byky1356)

摘　　要：目的：了解住院白血病患者生命质量与焦虑、抑郁的关系。方法：运用生存质量核心问卷和医院焦虑抑郁量表对56例白血病患者的生命质量、焦虑、抑郁状况进行调查分析。结果：56例白血病患者中,焦虑20例,抑郁18例。焦虑阳性组的总体健康状态、情绪功能和认知功能评分均低于焦虑阴性组（P〈0.05）,疲倦、疼痛和食欲丧失评分均高于焦虑阴性组（P〈0.01）;2组其他因子评分差异均无统计学意义（P〉0.05）。抑郁阳性组总体健康状态、角色功能、情绪功能、认知功能和社会功能评分均低于抑郁阴性组（P〈0.05-P〈0.01）,疲倦、疼痛、气促、失眠和食欲丧失评分均高于抑郁阴性组（P〈0.05-P〈0.01）;2组其他因子评分差异均无统计学意义（P〉0.05）。白血病患者的焦虑抑郁均与总体健康状态及角色、情绪、认知和社会功能呈负相关关系（P〈0.05-P〈0.01）,与疲倦、疼痛、气促、失眠和食欲丧失均呈正相关关系（P〈0.05-P〈0.01）;与其他因子均无相关关系（P〉0.05）。结论：住院白血病患者焦虑、抑郁发生率高,生命质量总体水平低。Objective： To investigate the correlations of quality of life with anxiety and depression in patients with leukemia. Methods：The quality of life, anxiety and depression in 56 patients with leukemia were investigated using the core quality of life questionnaire and hospital anxiety and depression scale. Results：Among 56 leukemia patients,20 cases with anxiety and 18 cases with depression were found. The scores of general health status, emotional and cognitive function in positive anxiety patients were lower than those in negative anxiety patients （ P 〈 0. 05 ）, but the scores of fatigue, pain and loss of appetite in positive anxiety patients were significantly high （ P 〈 0. 01 ）, and the differences of other factors scores between two groups were not statistically significant （ P 〉 0.05 ）. The scores of general health status, and role, emotional, cognitive and social function in positive anxiety patients were lower than those in negative anxiety patients （ P 〈 0. 05 to P 〈 0. 01 ）, but the scores of fatigue, pain, shortness of breath, insomnia,loss of appetite and depression in positive anxiety patients were significantly high （ P 〈 0.05 to P 〈 0.01 ） , and the differences of other factors scores between two groups were not statistically significant （ P 〉 0. 05 ）. The anxiety and depression in leukemia patients were negatively correlated to the general health status, and role, emotional, cognitive and social function （ P 〈 0. 05 to P 〈 0. 01 ）, and positively correlated to fatigue, pain, shortness of breath, insomnia and appetite loss （ P 〈 0. 05 to P 〈 0. 01 ）, and uncorrelated to other factors （ P 〉 0.05 ）. Conclusions ： The incidences of anxiety and depression in patients with leukemia are high and their overall qualities of life are low,which can provide a reference in improving the quality of life of patient by improving their anxiety and depression.

关 键 词：白血病 焦虑 抑郁 生命质量 

分 类 号：R733.7[医药卫生—肿瘤]