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作 者:杨宗霞[1,2] 李筱[1] 王莉[1] 李幼平[1] 唐雪莉[1]
机构地区:[1]四川大学华西医院中国循证医学中心,成都610041 [2]郫县中医医院,成都611730
出 处:《中国循证医学杂志》2015年第6期723-729,共7页Chinese Journal of Evidence-based Medicine
基 金:国家自然基金项目(编号:71073105)
摘 要:目的了解已有基于随机对照试验(RCT)的系统评价的质量评价工具,并比较其条目数及条目设置异同,为质量评价工具的优化和使用提供参考。方法计算机检索PubMed和EMbase数据库,纳入基于RCT的系统评价的质量评价工具,检索时限均为建库截至2013年12月。应用End Note X3、Excel 2010筛选、提取与整理数据。描述性分析系统评价质量评价工具的基本内容,比较不同类型质量评价工具的条目内容。结果最终纳入61篇文献,包括系统评价质量评价工具32个,其中方法学质量评价工具30个,报告质量评价工具2个。纳入工具于1984年-2007年由高等院校的医学研究机构、国家卫生服务和传播机构及著名流行病学家和方法学家等研发。32个工具中,4个为量表,其余28个为清单。纳入工具的条目数从5条-101条不等,其中9个工具条目数≥20条。结论系统评价和Meta分析质量评价工具多而杂,目前尚无统一高效的评判标准;不同质量评价工具的制作水平、条目内容、适用范围等不同,部分工具内容冗长不便应用;在指导实践和决策时,普遍存在适用面广而针对性不强的问题。如何规范系统评价质量评价工具,指导系统评价研究、实践与决策急需进一步研究。To comprehensively collect quality assessment tools of systematic review/meta-analysis(SR/MA) of randomized controlled trials(RCTs), and compare the differences of numbers and contents of items, in order to provide references for optimizing and using these quality assessment tools. Methods We searched Pub Med and EMbase databases up to December 31 th, 2013 for quality assessment tools of SR/MA of RCTs. End Note X3 software was used for screening literature and Excel 2010 software was used for data extraction. A descriptive analysis was performed. Results A total of 61 studies including 32 quality assessment tools were included. Among them, 30 tools were for methodological quality and 2 tools for reporting quality. These tools were developed by different medical universities or colleges, research institutes, national health institutes, and some famous epidemiologists and methodologists from 1984 to 2007. Among the 32 tools, 4 tools were scales, while 28 were checklists. The numbers of items of these tools ranged from 5 to 101, among them, 9 tools had more than 20 items. Conclusion There are many quality assessment tools for SR/MA, but none of them is generally acknowledged. The quality, contents of items, and applicability of these tools are different, and some of them are too long to use. In practice and decision-making, most of the tools have the problems of low relevance and applicability. How to regularly use these tools to guide the research, practice and decision-making of SR/MA is still needed to be further researched.
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