姜黄素类化合物不同提取方法的工艺优化和比较  

Optimization and comparison of different extraction methods of curcuminoids

作　　者：周培培[1] 杜欣韵 刘宁芝 王松林[1] 蒋建兰[1] 

机构地区：[1]天津市生物与制药工程重点实验室,天津大学化工学院制药工程系,天津300072

出　　处：《现代化工》2015年第6期132-135,共4页Modern Chemical Industry

基　　金：国家自然科学基金项目(81102900)

摘　　要：在单因素试验基础上,采用CCD响应面优化设计方法,以超声提取为例,研究超声提取、微波辅助提取与回流提取方法的最优工艺。结果表明,3种最优工艺的提取率分别为37.39、36.38、38.80 mg/g。经综合比较发现,超声提取具有时间短,提取率较高,操作方便等优势,可用于大规模生产。In order to obtain the most effective extraction process of curcuminoids, ultrasonic extraction, microwaveassisted extraction and reflux extraction are studied. On the basis of the single factor experiments, the three extraction methods are optimized by central composite design-response surface methodoXogy respectively, taking ultrasonic extraction as an example. The results indicate that the yield of curcuminoids under three conditions are 37.39,36. 38 and 38.80 mg/g （per gram of rhizomes powder）, respectively. By comprehensive comparison, ultrasonic extraction is found to be timesaving, efficient and handiness which may be utilized for industrial production.

关 键 词：姜黄 超声提取 微波辅助提取 回流提取 响应面设计 优化设计 

分 类 号：TQ461[化学工程—制药化工] R284.2[医药卫生—中药学]