食管套扎术治疗肝硬化致上消化道出血的分析  

Analysis of Hemorrhage of Upper Digestive Tract Caused by Esophageal Variceal Ligation in the Treatment of Liver Cirrhosis

作　　者：牛威[1] 杜霞霞 郭莲怡[1] 

机构地区：[1]辽宁医学院附属第一医院消化科 [2]辽宁医学院附属第三医院,辽宁锦州121001

出　　处：《辽宁医学院学报》2015年第3期25-28,I0001,共5页Journal of Liaoning Medical University (LNMU) Bimonthly

摘　　要：目的对内镜下食管套扎术治疗肝硬化致上消化道出血的疗效进行研究,为临床治疗提供指导。方法选取我院2011年12月至2013年12月间收治的因肝硬化导致上消化道出血的患者320例为研究对象,将其随机分为观察组和对照组,每组160例。对照组按常规予以药物治疗;观察组采用内镜下食管套扎法治疗。对两组治疗后的疗效、安全性及治疗依从率进行比较及统计学分析。结果研究中未出现死亡病例,观察组显效88例,有效58例,无效14例,总有效率为91.2%高于对照组的79.4%总有效率,且差异显著(P<0.05);观察组仅有10.0%的研究对象出现不良反应,不良反应发生率与对照组无显著差异性(P>0.05);观察组治疗依从性为92.5%优于81.9%的对照组治疗依从性,且具有显著差异(P<0.05)。结论在肝硬化致上消化道出血的治疗中食管套扎术较药物治疗具有疗效显著,安全性高,治疗依从性高等优势,适合临床推广应用。Objective To study hemorrhage of upper digestive tract caused by esophageal variceal ligation in the treatment of liv-er cirrhosis and provide guidance for clinical treatment. Methods 320 cases with upper gastrointestinal bleeding caused by liver cir-rhosis in our hospital from December 2011 to December 2013 were selected as the research object. They were randomly divided into ob-servation group and control group, with 160 cases in each group. The control group was given routine drug treatment, while the obser-vation group was given endoscopic variceal ligation. Then the efficacy, safety and compliance rate of the two groups were compared and statistically analyzed. Results There were no cases of death in the study, with 88 cases of remarkable improvement, 58 cases of ef-fectiveness, and 14 cases being invalid in the observation group. Thus the total effective rate of the observation group was 91. 2%, much higher than that of the control group whose total efficiency rate was 79. 4%. So the difference was statistically significant ( P<0. 05 ) . The incidence of adverse reactions in the observation group was 10%, with no significant difference compared with the control group ( P>0. 05 ) . The treatment compliance rate of observation group was 92. 5%, which was better than 81. 9% of the control group, with significant difference (P<0. 05). Conclusion In the treatment of liver cirrhosis caused by upper digestive tract hemor-rhage, compared with drug therapy, esophageal variceal ligation has significant curative effect with its higher safety and treatment com-pliance, and thus it is suitable for clinical application.

关 键 词：食管套扎术 肝硬化 上消化道出血 临床疗效 

分 类 号：R574.1[医药卫生—消化系统]