应用鼻咽癌放射治疗后颈淋巴转移复发的临床疗效观察  

Clinical application for neck lymph node metastasis and recurrence of nasopharyngeal carcinoma after radiotherapy

作　　者：张晶晶[1] 叶奕菁[1] 陆小军[1] 

机构地区：[1]中山大学附属中山医院肿瘤放疗科,广东中山528403

出　　处：《中国医学工程》2015年第3期6-7,共2页China Medical Engineering

基　　金：中山市科技计划项目(20132A083)

摘　　要：目的对应用鼻咽癌放射治疗后颈淋巴转移复发的临床疗效进行分析与研究。方法资料选自2005年12月-2014年1月在我院住院并接受放射治疗后颈部淋巴结转移复发的鼻咽癌患者28例,对其临床资料进行回顾与分析。给予所有患者实施根治性颈清扫术,再根据患者放射治疗后到手术治疗之间的间隔期、软组织是否存在侵犯、淋巴结的阳性情况以及性别、年龄等相关因素,将患者划分为2组,并对其生存率、显著性差异等进行分析。结果研究中颈淋巴转移复发的鼻咽癌患者当中,有7例死亡病例,1年生存率可达80.25%,3年生存率可达51.78%,5年生存率可达33.57%。结论针对鼻咽癌放射治疗后颈淋巴结转移复发的治疗,可选择根治性颈清扫术作为主要方式,对于软组织出现侵犯,或者是发生包膜浸润的患者,应补充放疗,以此方式提升其生存效率。[ Objective ] To analyze the effect of treatment methods to neck lymph node metastasis and recurrence after radiotherapy for nasopharyngeal carcinoma （NPC）. [ Methods ] Clinical data was selected since December 2005 to January 2014 in our hospital and 28 cases of NPC patients receiving radiotherapy with neck lymph node metastasis and recurrence. All the patients were performed with neck lymph node dissection. Then the clinical data was analyzed including the interval between surgery and radiotherapy, soft tissue invasion, the existence of positive lymph node and relevant factors such as age and gender. The patients were divided into two groups and survival difference was analyzed. [ Results ] Among all of NPC patients, 7 deaths, the survival rate of 1 year was 80.25%, 3 year survival rate could reach 51.78%, 5 year survival rate could reach 33.57%. [ Conclusion ] For the neck lymph node metastasis and recurrence of nasopharyngeal carcinoma after radiotherapy, radical neck lymph node dissection can be chosen as the main treatment method. Radiotherapy should be complemented for the patients with soft tissue invasion or capsular invasion.

关 键 词：鼻咽癌 放射治疗 颈淋巴结 转移复发 

分 类 号：R739.6[医药卫生—肿瘤]