乳腺疾病冷冻切片832例误诊与延迟诊断分析  

Misdiagnosis and Delayed Diagnosis of 832 Frozen Sections of Breast Diseases

作　　者：黄秋霞[1] 陈罡[1] 冯振博[1] 李祖云[1] 韦康来[1] 陈皓[1] 

机构地区：[1]广西医科大学第一附属医院病理科,南宁535021

出　　处：《解放军医药杂志》2015年第6期60-62,65,共4页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

摘　　要：目的评价乳腺疾病术中快速冷冻切片诊断的准确率,分析容易误诊、延迟诊断的疾病。方法对2009年8月—2014年9月832例乳腺疾病的术中快速冷冻切片与术后常规石蜡切片诊断结果进行回顾性分析。结果乳腺疾病术中冷冻切片确诊率为98.08%,误诊率为0.60%,均为假阴性,常见于良性叶状肿瘤、导管内乳头状瘤;延迟诊断率为1.32%,常见于导管内癌、导管内乳头状瘤、硬化性腺病。结论术中快速冷冻切片诊断对乳腺疾病术中定性有重要意义,提高对误诊、延迟疾病的认识水平,可提高准确率。Objective To investigate the accurate rate of quick frozen section in diagnosis of breast diseases, and to analyze the causes of misdiagnosis and delayed diagnosis. Methods The diagnosed results of 832 intraoperative frozen sections of breast disease and postoperative paraffin slices during August 2009 and September 2014 were retrospectively analyzed. Results The accurate rate of intraoperative frozen section was 98.08% , the misdiagnosis rate was 0. 60%. The misdiagnosed cases were false negative, and were commonly benign phyllodes tumor and intraductal papilloma; the rate of delayed diagnosis was 1.32% , and the delayed diagnosis cases were commonly intraductal carcinoma with sclerosing adenosis. Conclusion The intraoperative frozen sections in diagnosis of breast diseases can improve understanding the cause of misdiagnosis and delayed diagnosis and increase the accuracy rate of diagnosis.

关 键 词：乳腺疾病 冷冻切片 病理学 临床 误诊 延迟诊断 

分 类 号：R361.2[医药卫生—病理学] R655.8[医药卫生—基础医学]