23例原发性肺黏液表皮样癌外科诊疗及预后分析  

Diagnosis,surgical therapy and prognosis in patients with pulmonary mucoepidermoid carcinoma:An analysis of 23 cases

作　　者：王辉[1] 初向阳[1] 张连斌[1] 马克峰[1] 

机构地区：[1]解放军总医院胸外科,北京100853

出　　处：《解放军医学院学报》2015年第6期586-589,共4页Academic Journal of Chinese PLA Medical School

摘　　要：目的讨论原发性肺黏液表皮样癌(pulmonary mucoepidermoid carcinoma,PMEC)的临床特点、外科诊疗方法及预后。方法回顾性分析2005年7月-2014年7月23例在我院接受手术的PMEC患者的临床资料,对临床特征、诊断方法、治疗措施及预后进行分析。结果 23例中,高度恶性7例,低度恶性16例,均接受手术治疗,全肺切除4例,肺叶切除17例,开胸活检术2例。高度恶性组中位生存时间10个月,明显短于低度恶性组的44个月(P<0.01);高度恶性组淋巴结转移率明显高于低度恶性组的(71.4%vs 6.3%,P<0.01)。术后6例接受化疗。结论手术是治愈PMEC的唯一方法,其预后主要取决于恶性程度,高度恶性者预后差。Objective To discuss the clinical characteristic, diagnosis, surgical therapy and prognosis of primary pulmonary mucoepidermoid carcinoma （PMEC）. Methods Clinical data about 23 patients with PMEC who underwent surgery in our hospital from July 2005 to July 2014 were retrospectively analyzed. Results All 23 patients with PMEC had accepted surgery, including 4 cases with pneumonectomies, 17 cases with lobectomies and 2 cases with exploratory thoracotomies. There were 7 patients with high-grade PMEC and 16 patients with low-grade PMEC. The median survival time of patients with high-grade PMEC （10 months） was shorter than patients with low-grade PMEC （44 months） （P 〈 0.01）, and the constituent ratio of lymph node metastasis of patients with high-grade PMEC （71.4%） was higher than patients with low-grade PMEC （6.3%） （P 〈 0.01）. Six patients with PMEC received postoperative chemotherapy. Conclusion Surgery is the only way to cure PEMC. The prognosis of PMEC depends largely on the degree of malignancy, patients with high-grade PMEC have poor prognosis.

关 键 词：肺黏液表皮样癌 外科治疗 预后 

分 类 号：R734.2[医药卫生—肿瘤]