急性脑梗死患者血清非高密度脂蛋白胆固醇水平及其临床分析  

Clinical Significance of Serum Non-HDL-C Level in Acute Cerebral Infraction Patients

作　　者：杨森[1] 张珏[1] 陈建中[1] 

机构地区：[1]上海中医药大学附属曙光医院检验科,上海201203

出　　处：《标记免疫分析与临床》2015年第6期496-498,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：目的探讨血清非高密度脂蛋白胆固醇(non-HDL-C)水平在急性脑梗死(ACI)患者中的临床意义。方法收集ACI组96例,对照组98例,各组均测定血清总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白(HDL-C)和低密度脂蛋白(LDL-C)、载脂蛋白B(APOB),并计算出非高密度脂蛋白胆固醇(non-HDL-C)。结果 ACI组non-HDL-C、APOB、TC、TG、LDL-C水平明显高于正常对照组,HDL-水平显著低于对照组,各组间差异均有统计学意义(P<0.05),non-HDL-C与APOB、TC、TG、LDL-C呈正相关,与HDL-C呈负相关。结论 non-HDL-C可作为评价ACI危险程度的指标之一,应重视ACI和ACI高危人群血清non-HDL-C水平的检测。Objective To explore the clinical value of serum Non-HDL-C level in acute cerebral infraction （ACI） patients. Methods The serum levels of total cholesterol （TC）, triglyceride （TG）, high density lipoprotein cholesterol （ HDL- C ）, low density lipoprotein cholesterol （ LDL- C ） and apolipoprotein B （ APOB ） in 96 cases of ACI patients and 98 health controls were detected and non-HDL-C level was calculated. Results Compared with health controls, ACI group had significantly higher level in serum non- HDL- C, apoB, TC, TG, LDL- C and lower HDL- C levels （ P 〈 0.05 ）. The serum Non- HDL- C level was positively correlated with apoB, TC, TG and LDL- C, and negatively correlated with HDL-C. Conclusion The serum non-HDL-C levels is associated with ACI and might be as high risks index in the evaluation of ACI.

关 键 词：急性脑梗死 非高密度脂蛋白胆固醇 总胆固醇 高密度脂蛋白 载脂蛋白B 

分 类 号：R743.33[医药卫生—神经病学与精神病学]