错误相关负电位在精神科临床上推广——附50例正常成人分析  

PROMOTION OF ERROR-RELATED NEGATIVITY IN PSYCHIATRY——ATTACHING ANALYSIS OF 50 HEALTHY ADULTS

作　　者：杜向东[1] 张广亚[1] 殷铭[1] 杨勇[1] 潘雯[1] 董日霞[1] 李哲[1] 盖海军[1] 叶刚[1] 杨建功[1] 袁颖[1] 沈建红[1] 潘能荣 陈兴时[1] 殷光中[1] 

机构地区：[1]苏州市广济医院精神科,215008

出　　处：《现代电生理学杂志》2015年第2期70-72,81,共4页Journal of Modern Electrophysiology

基　　金：江苏省临床医学科技专项-新型临床诊疗技术攻关(BL2013018)

摘　　要：目的：应用引进的德国仪器及新技术探讨并建立健康成人错误相关负电位（ERN）的正常值。方法：应用德国Brain Products公司的ERP记录与分析系统，对50例21~55岁健康成人右利手受试者，作了ERN检测。结果：（1）32个头皮记录点皆在约100～150ms处出现了一个负波，健康成人ERN波形较稳定。（2）在Cz、Fz、Pz、C3、C45个脑区，建立了健康成人ERN潜伏期和波幅均值。（3）左右侧比较及男女性别比较差异无统计学意义（P〉0．05）。结论：健康成人ERN较稳定和可靠。ERN可作为一个有临床推广应用价值的ERP而用于神经精神科临床。Objective： To explore and establish Error-related Negativity（ERN） normal value of healthy adults. Methods： ERN was tested in 50 heathy （21-55 years old） right handedness adults by Germany Brain Products company recording and analyzing system. Results： （1） Negative wave was recorded between 100 and 150ms in all the 32 scalp recording points. The shape of healthy adults＇ ERN wave was stable. （2） The average ERN latency and amplitude value of healthy adults at the brain area of Cz, Fz, Pz,C3 and C4 was established. （3） The variance between right and left side of brain and the man and the woman wasn＇t significant（P〉0.05） . Conclusion： ERN of healthy adults is stable and reliable and can be used as a valuable ERP application in psychiatric clinic.

关 键 词：健康成人 错误相关负电位 正常值 

分 类 号：R749[医药卫生—神经病学与精神病学]