重庆市渝北区社区海洛因依赖者HIV、HCV和梅毒感染状况分析  

Analysis on infection status of HIV,HCV and syphilis among community heroin abusers

作　　者：龚斌 朱千[2] 唐莎莎 高才琴 杨德玲 

机构地区：[1]重庆市渝北区第二人民医院美沙酮门诊,重庆市400147 [2]遵义医学院医学心理学教研室,遵义市563003

出　　处：《中国药物滥用防治杂志》2015年第3期129-132,共4页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：遵义医学院博士启动基金项目(基金号FB-2014-4)

摘　　要：目的:分析社区海洛因依赖者的HIV、HCV、梅毒等血源性传染病的感染状况,为采取针对性干预措施提供依据。方法:调查重庆市渝北区美沙酮门诊378例海洛因依赖者的一般人口学资料,并收集血液样本进行血清学检测,分析病人的人口学特征、感染状况和不同特征之间感染率的差异。结果:在调查的依赖者中,至少77.2%感染HIV、HCV和梅毒3种传染病中的1种,其中HIV、HCV与梅毒的感染率分别为1.85%、75.9%和12.2%。二分类的Logistic回归分析结果显示,年龄/共用注射器、是否注射以及性别分别是影响HIV、HCV和梅毒感染的危险因素。结论:重庆市渝北区社区海洛因依赖者HCV感染率较高,HCV和梅毒合并感染率较高,应积极对该人群开展感染者针具交换和心理行为干预。Objective：To analyze the infection status of blood-borne infectious diseases such as HIV,HCV and syphilis among the community heroin abusers,to provide the basis for purposeful intervention measures.Methods：The general demographic information of 378 heroin abusers in Yubei District,Chongqing City was investigated,and the blood samples were collected for serology tests to analyze the differences on the features of the general demographic information,infection status,and the different infection rates among the heroin abusers.Results：The infect rate was 77.2%（292/378） in the community heroin abusers infected at least one of the three kinds of viruses for HIV,HCV and syphilis,the infect rates of HIV,HCV and syphilis were 1.85%（7/378）,75.9%（287/378） and12.2%（46/378）,respectively.There were statistical significances for HCV infection rate among the factors of age,the current way of taking drug,sharing injector,injection or not,drug-tanking of spouse or sex partner（P〈0.05 or P〈0.001）,of which the infection rates for factors of age from 30 to 40（86.51%）,injection and mouth-taking drug（95.65%）,injection（89.05%）,spouse or sex partner injection（91.49%） were relatively high;there were statistical significances for syphilis infection rate among the factors of gender,marital status（P〈0.05 or P〈0.001）,of which the infection rates for factors of female（21.82%）,cohabitation（36.36%）were relatively high.The results of the binary logistic regression showed that age/sharing injector,injection or not,and gender were the danger factors of infecting HIV,HCV and syphilis,respectively.Conclusion：The infection rates of HCV and the HCV combined with syphilis among community heroin abusers in Yubei District,Chongqing City are relatively high.The hospital should actively carry out the needle-change work and psycho-behavioral intervention programs among the community heroin abusers.

关 键 词：社区药物维持治疗 海洛因依赖 HIV HCV 梅毒 

分 类 号：R749.64[医药卫生—神经病学与精神病学]