126例男性脑卒中患者勃起功能障碍及影响因素分析  

Prevalence and risk factors of erectile dysfunction in 126 cases of male post-stroke patients

作　　者：辛家厚[1] 俞明明[1] 程晋宝 汪青松[1] 

机构地区：[1]安徽省合肥市解放军第一〇五医院神经内科,安徽合肥230031 [2]安徽省合肥市解放军第一〇五医院生殖中心,安徽合肥230031

出　　处：《重庆医学》2015年第18期2501-2503,共3页Chongqing medicine

摘　　要：目的探讨男性脑卒中患者勃起功能障碍(ED)发生情况及影响因素。方法选取126例男性脑卒中患者,采用国际勃起功能指数-5(IIEF-5)量表判定入选患者有无ED,根据评分结果将患者分为ED组和非ED组。采用NIHSS评分量表及改良Rankin(mRS)评分量表评估患者神经功能缺损情况;采用抑郁自评量表(HAMD)评估患者抑郁状态;采用简易智能状态检查量表(MMSE)评估患者认知功能。比较ED组与非ED组临床因素及心理因素组间的差异,应用Logistic回归模型分析ED的影响因素。结果共有38例(30.2%)患者患有ED。单因素分析显示高血压、糖尿病、血管紧张素转化酶抑制剂(ACEI)药物使用及抑郁与ED显著相关,而多因素分析提示ACEI药物使用及抑郁与ED独立相关。结论男性脑卒中患者的ED较为常见,患者使用ACEI药物及抑郁是ED主要影响因素。Objective The aim of this study was to investigate the prevalence of erectile dysfunction （ED） and to assess the risk factors of ED in male post‐stroke patients .Methods One hundred and twenty six male post‐stroke patients were invited to par‐ticipate in this study .Patients were divided into ED group and non‐ED group according to the erectile function evaluated by Interna‐tional Index of Erectile Function‐5 （IIEF‐5） .The neurological impairment was measured using the National Institute of Health Stroke Scale （NIHSS） and the modified Rankin Scale （mRS） .Depressive symptoms was measured using the Hamilton Depression Scales （HAMD） .The global cognitive function was measured using the Mini mental Status Examination （MMSE） .The clinical and psychosocial factors were compared between the ED and non‐ED groups .Univariate and multivariate Logistic regression analyses were employed to assess the risk factors with ED .Results There were 38 patients （30 .2% ） with ED in all the 126 male post‐stroke patients .Univariate Logistic regression analyses revealed that hypertension ,diabetes ,ACEI ,and depression were significantly related to ED in male post‐stroke patients （P〈0 .05） .Multivariate Logistic regression analyses revealed that ACEI and depression were independently associated with ED in male post‐stroke patients （P〈0 .05） .Conclusion ED is common in Chinese male post‐stroke patients .ACEI and depression are the major determinants of ED .

关 键 词：卒中 勃起功能障碍 危险因素 抑郁症 

分 类 号：R743.3[医药卫生—神经病学与精神病学]