基于Apriori算法挖掘经验方的“前N组”法  

The “top N groups”method used to mine the empirical formula based on Apriori algorithm

作　　者：徐亮[1] 袁锋[2] 陈守强[3] 毕文霞[1] 侯建辉[1] 

机构地区：[1]山东中医药大学,本硕连读生2009级济南250014 [2]山东管理学院信息工程学院,济南250001 [3]山东中医药大学第二附属医院心脏中心,济南250001

出　　处：《光明中医》2015年第6期1181-1183,共3页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：目的基于Apriori算法,通过"前N组"法挖掘医家经验方。方法将陈守强副主任医师的2647份病历输入电子病历管理系统[1],通过Apriori算法挖掘出其治疗冠心病的高频中药组合,以药味最多的组合为母板,加入与前N组高频中药组合中不同的中药,从而总结出经验方。结果挖掘出的经验方由川芎、丹参、甘草、黄芪、木香、麦冬、五味子、焦三仙、黄连、连翘10味中药组成,与其临床常用的胸痹2号方类似。结论该方法在名老中医经验传承中具有一定的意义,值得推广。Objective Based on Apriori algorithm , mine the medical empirical formula by “top N groups” method.Methods input the 2, 647 medical records of Chen Shouqiang , Associate Chief Physician , into the electronic medical records management system;mine the high-frequency combination of traditional Chinese medicine for treatment of coronary heart disease via the Apriori algorithm ;take the combination with most kinds of herbal medicines as the motherboard , and then add Chinese medicine different from what included in the top N groups of high-frequency combinations of traditional Chinese medicine; thus we can sum up the empirical formula .Results the empirical formula mined consists of 10 herbs （i.e.rhizome of Ligusticum wallichii, salvia miltiorrhiza, licorice Roots Northwest Origin, radix astragali, Costustoot , tuber of dwarf lilyturf , Schisandra chinensis , charred triplet , Coptis chinensis and fructus forsythiae ） , which is similar with the chest stuffiness No .2 formula commonly used in clinic .Conclusion This method has some significance in the experience heritage of distinguished veteran doctors of TCM , and it is worth promoting .

关 键 词：经验方 名老中医 APRIORI算法 “前N组”法 

分 类 号：R289[医药卫生—方剂学]