非对映选择性一锅八组分反应高效绿色合成二螺氢喹啉（英文）  

An efficient green synthesis of dispirohydroquinolines via a diastereoselective one-pot eight-component reaction

作　　者：Sajjad Salahi Malek Taher Maghsoodlou Nourallah Hazeri Mojtaba Lashkari Santiago Garcia-Granda Laura Torre-Fernandez 

机构地区：[1]Department of Chemistry,Faculty of Science,University of Sistan and Baluchestan [2]Department of Physical and Analytical Chemistry,University of Oviedo-CINN

出　　处：《催化学报》2015年第7期1023-1028,共6页

基　　金：the funding support received for this project from the Research Council of the University of Sistan and Baluchestan;partially supported by FEDER funding, the Spanish Ministerio de Economía y Competitividad MAT2006–01997,MAT2010-15094 and the Factoría de Cristalización(Consolider Ingenio 2010)

摘　　要：The one-pot eight-component reaction between Meldrum's acid, an aromatic aldehyde, and an aryl amine was achieved in the presence of citric acid catalyst. The corresponding dispirohydroquinolines were obtained in good yields with excellent diastereoselectivity. This method is a combination of the Knoevenagel and Michael reactions.The one-pot eight-component reaction between Meldrum＇s acid, an aromatic aldehyde, and an aryl amine was achieved in the presence of citric acid catalyst. The corresponding dispirohydroquinolines were obtained in good yields with excellent diastereoselectivity. This method is a combination of the Knoevenagel and Michael reactions.

关 键 词：KNOEVENAGEL反应 非对映选择性 绿色合成 组分 Meldrum酸 锅 酸催化剂 芳香醛 

分 类 号：O626.323[理学—有机化学]