奥氮平对女性精神分裂症患者主观睡眠的影响  

The Impact of Olanzapine on Subjective Sleep in Female Patients with Schizophrenia

作　　者：王亚丽[1] 石玉中[1] 娄百玉[1] 娄和玲 

机构地区：[1]河南省新乡医学院第二附属医院精神科,河南新乡453002

出　　处：《中国伤残医学》2015年第13期17-18,共2页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：探讨奥氮平对精神分裂症患者睡眠的影响。方法：选择符合ICD-10诊断标准的首发的女性精神分裂症患者70例，给予奥氮平单一用药治疗，用药前及用药4周后用匹兹堡睡眠质量指标量表（PSQI）评定患者的主观睡眠状况。应用SPSS17．0统计软件包进行统计分析。结果：患者服药后较服药前总睡眠时间、睡眠潜伏期、睡眠效率、觉醒时间、快眼动睡眠潜伏期、快眼动睡眠时间都有明显改善。结论：精神分裂症患者存在有睡眠障碍，睡眠时间缩短，睡眠质量下降。奥氮平可以改善精神分裂症患者的睡眠，可以延长睡眠时间，提高睡眠质量。Objective： To investigate the effect of olanzapine on sleep in patients with schizophrenia. Methods： 70 cases of female pa- tients with schizophrenia first meets the diagnostic criteria of ICD - 10, given olanzapine monotherapy treatment, after four weeks before treatment and medication subjective assessment of sleep in patients with the Pittsburgh Sleep Quality Index Scale （PSQI） . Application SPSS17.0 statistical software package for statistical analysis. Results ： The compared with patients after taking＇the medication before the total sleep time, sleep latency, sleep efficiency, wake time, rapid eye movement sleep latency, rapid eye movement sleep time has improved significantly. Conclusion： Schizophrenia patients with sleep disorders, sleep time, sleep quality. Olanzapine may improve sleep in patients with schizophrenia can be extended sleep time, improve sleep quality.

关 键 词：奥氮平 精神分裂症 PSQI 

分 类 号：R749.3[医药卫生—神经病学与精神病学]