中医体质类型与非酒精性脂肪性肝病临床分型及超声分度的相关性  

Correlation of Chinese Medical Constitution Types with Clinical Classification and Ultrasound Grading of Nonalcoholic Fatty Liver Disease

作　　者：杨艳娜[1] 张灵芝[1] 江静华[1] 

机构地区：[1]广州中医药大学附属中山中医院,广东中山528400

出　　处：《新中医》2015年第7期81-83,共3页New Chinese Medicine

基　　金：广东省中山市科技局基金资助项目(20132A165)

摘　　要：目的:探讨中医体质类型与非酒精性脂肪性肝病(NAFLD)临床分型及超声分度的相关性。方法:对933例NAFLD患者进行临床分型和超声分度检查,并采用标准化中医体质分类量表辨识患者中医体质,分析NAFLD临床分型及超声分度与中医体质类型的相关性。结果:临床分型中,非酒精性单纯性脂肪肝及非酒精性脂肪性肝炎患者的偏颇体质均以湿热质、痰湿质、血瘀质为主。NAFLD患者的偏颇体质在不同的临床分型的差异有统计学意义(P<0.01)。超声分度中,轻度脂肪肝患者以湿热质、痰湿质、血瘀质为主;中度脂肪肝患者以痰湿质、湿热质和血瘀质为主;重度脂肪肝患者仅发生在痰湿质、湿热质、血瘀质及气郁质中。超声分度不同患者的体质分型的差异有统计学意义(P<0.05)。结论:中医体质类型与NAFLD临床分型及超声分度存在相关性。Objective. To explore the correlation of Chinese medical constitution types with clinical classification and ultrasound grading of nonalcoholic fatty liver disease（NAFLD）. Methods= The clinical classification and ultrasound grading were carried out in 933 NAFLD patients, and standardized classification measurement questionnaire of nine constitutions in Chinese medicine was used to investigate the constitution types of the NAFLD patients. The correlation of Chinese medical constitution types with clinical classification and ultrasound grading of NAFLD patients was analyzed. Results：The biased constitution patients with nonalcoholic fatty liver（NAFL） and non-alcoholic steatosis hepatitis（NASH）were mostly dominated by damp heat, phlegm dampness and blood stasis. The differences among the biased constitution patients with NAFLD had statistical significance（P 〈 0.01）. The results of ultrasound grading showed that mild NAFL patients were dominated by the constitution types of damp heat, phlegm dampness and blood stasis, mild NAFL patients were dominated by phlegm dampness, damp heat and blood stasis, and severe NAFL patients were dominated by phlegm dampness, damp heat, blood stasis and qi stagnation in order. The differences among the constitution types of NAFLD patients with different ultrasound grading had statistical significance（P 〈 0.05）. Conclusion： Chinese medical constitution types of NAFLD patients were correlated with their clinical classification and ultrasound grading.

关 键 词：非酒精性脂肪性肝病(NAFLD) 中医体质类型 临床分型 超声分度 相关性 

分 类 号：R575.6[医药卫生—消化系统]