服用奥美拉唑患者用药知识、用药依从性的调查  

Investigation of medication knowledge, compliance and drug efficacy of patients taking omeprazole

作　　者：吴志平[1] 谢瑞霞[1] 丁界先 齐国卿[1] 王小英[1] 危蓉[1] 李佩蓉 张德奎[1] 

机构地区：[1]兰州大学第二医院消化科,甘肃兰州730030

出　　处：《兰州大学学报（医学版）》2015年第3期31-35,共5页Journal of Lanzhou University（Medical Sciences）

基　　金：甘肃省卫生行业科研计划项目(GSWST2011-08)

摘　　要：目的调查服用奥美拉唑患者对该药物用药知识的掌握情况及用药依从性,并探究用药知识掌握情况、用药依从性与药物疗效间的关系。方法自制调查问卷,随机对就诊于兰州大学第二医院和临夏回族自治州广河县人民医院630例正在服用或曾经服用过奥美拉唑的患者进行问卷调查。使用Epi Data 3.1录入问卷,SPSS 22.0分析调查结果,统计方法采用Spearman相关分析和序次logistic回归分析。结果 38%的患者能基本掌握奥美拉唑的用药知识,16.2%的患者有良好的用药依从性,65.6%的患者认为该药有效。不同性别、年龄、居住地和职业的患者对奥美拉唑用药知识的掌握情况存在明显差异,女性优于男性、青年人优于中老年人、多民族杂居城市优于回民聚居县城、公务员及高技术职业优于基础职业。患者对奥美拉唑用药知识的掌握情况、患者的用药依从性、患者对服用奥美拉唑的用药疗效自评三者间存在正相关。结论患者对奥美拉唑用药知识的掌握情况、用药依从性均较差,两者间存在协同性,丰富的用药知识与良好的用药依从性对充分发挥药物的疗效有积极的影响。Objective To investigate medicine knowledge and compliance, among patients taking omeprazole, and to explore relationships among their medication knowledge, compliance, and drug efficacy. Methods A survey using self-made questionnaire was conducted on 630 outpatients, who were taking or had taken omeprazole, from the Second Hospital of Lanzhou University and People＇s Hospital of Guanghe County in Linxia Hui Autonomous Prefecture. The questionnaire includes the basic information of the patients, drug basic knowledge and evaluation conten. EpiData 3.1 was used to keep records from the questionnaire and SPSS 22.0 was employed to analyze survey results by Spearman correlation analysis and logistic regression analysis. Results In the survey, 38%of patients taking omeprazole could master basic knowledge of drug, 16.2%omeprazole users have good medication compliance, 65.6%patients taking omeprazole consider it effective. There are significantly differentcebetween different gender, age, residence and occupation of patients in the mastery of medication knowledge for omeprazole, namely, women is better than men, young people better than the elderly, multi-ethnic inhabited city, better than Hui nationality gathering county, the superior civil servants and high-tech occupation better than the basic occupation. And significant positive correlation was found among the medication knowledge of omeprazole, the patient＇s compliance with medication and the patient＇s self-assessment of efficacy to omeprazole. Conclusion At present, omeprazole users generally had a poor mastery of medication knowledge and compliance, and these two factors were correlated. Rich medica-tion knowledge and good medication compliance have a positive impact on omeprazole＇s efficacy.

关 键 词：奥美拉唑 用药知识 依从性 药物疗效 

分 类 号：R573[医药卫生—消化系统]