克罗恩病患者合并院内感染的危险因素分析  

Risk factors for nosocomial infections in patients with Crohn's disease

作　　者：杨少武[1] 吴刚[1] 

机构地区：[1]天门市第一人民医院药剂科,天门市431700

出　　处：《中华实验和临床感染病杂志（电子版）》2015年第3期89-91,共3页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

摘　　要：目的探讨克罗恩病(CD)患者并发医院感染相关因素,为临床诊疗工作提供参考。方法对住院治疗的120例CD患者的临床资料进行比较分析;与医院感染有显著差异的因素再进行多元Logistic回归分析。结果 CD患者医院感染率为38.3%(46/120),医院获得性肺炎为32.6%(15/46);疾病行为、活动指数(CDAI)、营养不良、使用激素或免疫抑制剂等均是并发院内感染的危险因素(P均<0.05),其OR值分别为2.25、3.62、2.82、2.18和2.58。结论对于克罗恩病,临床中应综合考虑上述危险因素,做好感染的预防、治疗和护理工作。Objective To explore the risk factors for Crohn＇s disease （CD） patients with nosocomial infection, and to provide guidance for the clinical diagnosis and treatment. Methods The clinical data of 120 cases of CD were analyzed by using comparative analysis, retrospectively. The significantly related factors with nosocomial infection were analyzed by a multivariable Logistic regression. Results The incidence rate with nosocomial infection was 38.3%, there was 32.6% （15/46） CD patient with hospital acquired pneumonia. The disease behavior, Crohn＇s disease activity index （CDAI）, malnutrition, the use of corticoid and the use of immunosuppressive agents were the risk factors of CD patient with nosocomial infection （P all 〈 0.05）, and the OR values were 2.25, 3.62, 2.82, 2.18 and 2.58, respectively. Conclusions It is necessary for the medical staff to comprehensively consider these risk factors and take effective prevention, treatment and nursing measures.

关 键 词：克罗恩病 院内感染 危险因素 

分 类 号：R574[医药卫生—消化系统]