阿立哌唑和氟哌啶醇治疗脑外伤所致精神障碍疗效对比  

Comparative Efficacy of Aripiprazole and Haloperidol in Treatment of Cerebral Trauma Mental Disorder

作　　者：董勇[1] 关靖宇[2] 

机构地区：[1]沈阳市精神卫生中心,110168 [2]沈阳军区总医院神经外科,110000

出　　处：《中国继续医学教育》2015年第15期161-162,共2页China Continuing Medical Education

摘　　要：目的比较阿立哌唑和氟哌啶醇治疗脑外伤所致精神障碍的临床疗效。方法将2010年3月~2013年3月72例在我院治疗的脑外伤所致精神障碍患者随机分为阿立哌唑组与氟哌啶醇组,每组各36例,评定治疗效果。结果阿立哌唑在治疗脑外伤所致的精神障碍时总体疗效与氟哌啶醇相当,差异不明显（P〉0.05）,阿立哌唑组的不良反应发生率低于氟哌啶醇组,差异显著（P〈0.01）。结论阿立哌唑治疗脑外伤所致精神障碍安全性高。Objective To compare the clinical efficacy of aripiprazole and haloperidol in the treatment of mental disorders due to brain trauma. Methods From 2010 March ~ 2013 March 72 cases of patients with mental disorders caused by cerebral trauma were randomly divided into aripiprazole group and haloperidol group, each of the 36 cases, compare the therapeutic effects. Results Two kinds of drugs in the treatment of mental disorders due to brain injury is the overall curative effect, the difference was not significant（P〈0.05）. The adverse reaction of aripiprazole group were significantly lower than those in haloperidol group, the difference was significant（P〈0.01）. Conclusion Aripiprazole in the treatment of mental disorders due to brain injury has good curative effectand high safety.

关 键 词：阿立哌唑 氟哌啶醇 脑外伤 精神障碍 

分 类 号：R749.1[医药卫生—神经病学与精神病学]