顺铂联合希罗达方案与奥沙利铂联合希罗达方案治疗晚期胃癌的疗效分析  

Curative Effect Analysis of Cisplatin Combined with Xeloda Scheme and Oxaliplatin Combined with Xeloda Scheme in the Treatment of Advanced Gastric Cancer

作　　者：林菜梅 罗泽民[1] 罗燕娜[1] 李勇[1] 池海波[1] 陈洪毅[1] 

机构地区：[1]广东省农垦中心医院肿瘤中西医结合病区,广东湛江524002

出　　处：《黑龙江医学》2015年第4期431-432,共2页Heilongjiang Medical Journal

摘　　要：目的观察晚期胃癌患者接受不同化疗方案的治疗效果,以此为临床提供有效的治疗参考依据。方法取我院收治的64例晚期胃癌患者为本次研究对象,根据治疗方法不同将其均分为对照组与实验组,每组各32例,给予对照组顺铂与希罗达联合用药治疗,给予实验组患者奥沙利铂与希罗达联合用药治疗,观察两组治疗效果并作统计学分析。结果两组治疗效果无显著差异,不具有统计学意义(P>0.05);与对照组相比,实验组患者不良反应发生率更低,组间差异具有统计学意义(P<0.05)。结论在晚期胃癌的临床治疗方案中,奥沙利铂联合希罗达方案效果确切,安全有效,不良反应较少,值得临床推广使用。Objective To observe the treatment effect of different chemotherapy schemes in the patients with advanced gastric cancer so as to provide effective reference for clinical application. Methods In the present study,64 cases of advanced gastric cancer patients admitted to the hospital were served as the research subjects. According to the different treatment methods,the patients were divided into the control group and the experimental group with 32 cases in each group,of which the combined cisplatin and shiroda were treated on the control group,and the combined oxaliplatin and xeloda were treated on the experimental group. The therapeutic effect of the two groups was observed,and statistical analysis was conducted. Results There was no significant difference in the therapeutic effect of the two groups,which showed no statistical significance（ P〉 0. 05）. Compared with that of the control group,the patients in the experimental group had lower adverse reaction rate,and the differences between the two groups were statistically significant（ P 〈0. 05）. Conclusion In the clinical treatment schemes of advanced gastric cancer,the scheme of oxaliplatin combined with xeloda has definite effect,and it is safe and effective and less adverse reactions,so it is worthy of clinical promotion and application.

关 键 词：晚期胃癌 希罗达 顺铂 奥沙利铂 疗效 

分 类 号：R735.2[医药卫生—肿瘤]