乳腺和结肠同时性双原发癌1例临床病理分析及文献复习  

Double primary breast carcinoma and colon carcinoma: a case report and literature review

作　　者：蒲霞[1] 夏天[1] 郭庆喜[1] 肖秀丽[1] 

机构地区：[1]泸州医学院附属医院病理科,四川泸州646000

出　　处：《泸州医学院学报》2015年第3期283-285,共3页Journal of Luzhou Medical College

摘　　要：目的:探讨乳腺和结肠双原发癌的临床病理特征。方法:对1例诊断为乳腺和结肠双原发癌患者的临床资料、组织学形态及免疫组化结果进行分析,并对相关文献进行复习。结果:本例为乳腺和结肠双原发癌,病理学活体组织检查证实为"左乳腺"浸润性导管癌(WHO II级)和右半结肠隆起型高分化腺癌,免疫组化:左乳腺癌组织ER(+)、PR(+)、P120(+)、CK20(-)、P53(-),右半结肠癌组织P53(+)、Nm23(+)、CK20(+)、villin(+)。结论:乳腺和结肠双原发癌为罕见的病例,临床易误诊为肿瘤转移而误治,积累乳腺和结直肠双原发癌临床病理及免疫表型资料,避免临床误诊误治具有重要的价值。Objective： To discuss the clinicopathologic features of synchronous primary breast carcinoma and colon carcinoma. Methods： The clinical data,pathological diagnosis and immunohistochemical results of a case of double primary breast carcinoma and colon carcinoma were analyzed, meanwhile the related literatures were reviewed. Results： This case was a double primary breast carcinoma and colon carcinoma; CT scan showed a colon tumor and mammary gland molybdenum target revealed an irregular calcification shadow with axillary lymph node enlargement. Histopathological examination found two different kinds of tumors, breast carcinoma and colon carcinoma; breast cancer cells were positive for ER, PR, P120; colon cancer cells were positive for P53,Nm23, CEA, Villin, CK20. Conclusions： Synchronous primary breast carcinoma and colon carcinoma is rare. It usually lacks of typical clinical symptom and is easy to be missed diagnosed or misdiagnosed, so careful histopathological examination and immunohistochemical exam are very important for the correct diagnosis.

关 键 词：双原发癌 乳腺浸润性导管癌 结直肠癌 临床病理分析 

分 类 号：R361.2[医药卫生—病理学] R365[医药卫生—基础医学]