术中磁共振技术辅助手术治疗脑深部胶质瘤的疗效分析  

Efficacy of intraoperative MRI in treatment of patients with deep-seated gliomas

作　　者：张猛[1,2] 马晓东[1] 余新光[1] 余鹏霄 王强[1] 徐维林[1] 张宏伟[1] 

机构地区：[1]解放军总医院神经外科,北京100853 [2]广州军区第四二五医院,海南三亚572000

出　　处：《解放军医学院学报》2015年第7期691-693,698,共4页Academic Journal of Chinese PLA Medical School

摘　　要：目的分析术中磁共振技术在脑深部胶质瘤辅助手术中的疗效。方法回顾性研究解放军总医院2005年1月-2014年12月450例脑深部胶质瘤病例,比较术中磁共振组与传统显微手术结合功能导航组全切率的差异。结果不同部位脑深部胶质瘤的手术方式偏好不同。两组中未见年龄、性别及病理分级差异。术中磁共振组于丘脑基底节区(75.6%)、胼胝体区(83.8%)、脑室及周边区(76%)的全切率分别高于对应的传统手术组(71.0%、76.9%、50%),但除脑室及周边区外,两组其他部位全切率差异无统计学意义。高级别及低级别脑深部胶质瘤全切率差异也未见统计学意义。结论术中磁共振辅助技术在脑室及周边区可实现较高的全切率。Objective To analyze the efficacy of intraoperative MRI technique in treatment of patients with deep-seated gliomas. Methods Four hundred and fifty cases with deep-seated gliomas in Chinese PLA General Hospital from January 2005 to December 2014 were collected and retrospectively studied to compare the total resection rate （TRR） between conventional microsurgery combined with functional neural navigation group and intraoperative MRI group. Results Preferential options of surgical technique were found among the various locations of deep-seated gliomas. There was no difference in age, gender and pathological grade between the two groups. TRR of intraoperative MRI group was higher in the region of thalamus-basal ganglia （75.6%）, callosum （83.8%） and surroundings of ventricle （76%） than those of conventional groups （71.0%, 76.9%, 50.0%）, no statistically significant differences were found except for ventricle and surrounding regions. Also, TRR was of no statistically significant difference between the two groups neither in high grade gliomas nor in low grade gliomas. Conclusion Intraoperative MRI achieves higher TRR in the region of surroundings of ventricle.

关 键 词：术中磁共振 神经导航 脑深部胶质瘤 外科手术 

分 类 号：R739.41[医药卫生—肿瘤]