基于红外检测乳腺肿瘤的多参数反演研究  

Investigation of Multivariable Estimation in Breast Tumor Diagnosis by Infrared Thermography

作　　者：黄鉴[1] 卢玫[1] 李博汉[1] 张涛[1] 

机构地区：[1]上海理工大学能源与动力工程学院,上海200093

出　　处：《生物医学工程研究》2015年第2期74-79,共6页Journal Of Biomedical Engineering Research

基　　金：国家自然科学基金资助项目(51176126)

摘　　要：根据红外热像仪测得的体表温度来获得肿瘤相关信息,可以抽象为一个含有内热源的导热反问题。针对同时反演肿瘤位置、肿瘤代谢热强度及乳腺导热系数等多参数反问题的特点,本研究提出并建立了与反演参数相关的辅助目标函数,同时对求解所采用的粒子群优化算法中的更新方式进行了相应的改进。数值验证结果表明:在反演多参数反问题中采用多目标函数能提高反演精度,加快收敛速度。研究结果为根据乳腺红外热像图量化诊断体内肿瘤提供了理论依据。Medical infrared thermography is a non -contact,non -invasive imaging method that applied in the area of breast canc-er detection.With thermogram,parameters of tumor inside can be estimated,and an inverse heat conduction model with inner heat source was obtained from it.Embark upon the situation that inverse heat conduction problem has multi variables,tumor position,meta-bolic heat generation rate and thermal conductivity,two more assistant fitness function were established base on how heat source posi-tion and conductivity influence the surface temperature,and Particle Swarm Optimization was modified to solve the multivariable inverse problem.Numerical verification showed that the method was suitable for breast tumor properties estimation,and the modified PSO with multi fitness functions improved the accuracy and shortened the solution time.The results provide theoretical basis for quantitative diag-nosis of breast tumor by infrared thermal images.

关 键 词：乳腺肿瘤 红外检测 多参数反问题 多目标函数 粒子群算法 

分 类 号：TK124[动力工程及工程热物理—工程热物理] R318[动力工程及工程热物理—热能工程]