直肠癌根治性放疗合成计划设计的剂量学分析  

Analysis of Radiation Synthesis Planning Dosimetry for Radical Rectal Cancer

作　　者：杨昕[1] 丁叔波[1] 胡望远[1] 孙红娟[1] 黎萍[1] 

机构地区：[1]金华市中心医院,浙江金华321000

出　　处：《肿瘤学杂志》2015年第6期487-490,共4页Journal of Chinese Oncology

基　　金：金华市科学技术研究项目(2012-3-010)

摘　　要：[目的]比较适形与调强基础上合成叠加调强计划的剂量学差异。[方法]选取根治性放疗直肠癌靶区,第一程计划分别用3野适形、4野适形和5野调强对PTV给予50Gy,在第一程计划基础上合成调强计划(IMRT)给予PGTV到66Gy根治剂量。危及器官都不超量的情况下比较靶区等效生物剂量。[结果]3个叠加后计划无明显差异。不考虑第一程计划,第二程计划差异明显,PGTV 95%剂量:5野剂量为15Gy,4野剂量为13.18Gy,3野剂量为8.82Gy。[结论]直肠癌根治性放疗局部加量调强基础上的合成计划等效生物剂量更接近预期值。[Purpose] To compare the dosimetry difference of conformal and intensity modulated synthesis based on the superposition of IMRT. [Methods] The radical radiotherapy target region was selected. The first process plan was respectively for 3 field conformal,given 50 Gy PTV to do the 4 field conformal and intensity-modulated 5.PGTV was given the 66 Gy radical dose in the first process plan based on the synthesis of IMRT plan. Crisis organ were not excessive compared with the case of the target area of biological effective dose.[Results] Three superimposed plans had no difference.Regardless of the first process plan,the second process was significantly different,PGTV 95% dose：5 field,15Gy;4 field,13.18Gy;3 field dose,8.82 Gy. [Conclusion]Synthetic plan of biological effective dose of rectal cancer after radical radiotherapy based on local modulated is closer to the default value.

关 键 词：直肠肿瘤 放射治疗 

分 类 号：R735.31[医药卫生—肿瘤]