microRNA和食管癌关系的研究进展  

Research advances in the relationship between microRNA and esophageal cancer

作　　者：江文洋[1] 任杰[2] 范国华[1] 康敢军[1] 陈蕾[1] 

机构地区：[1]武汉大学人民医院胸外科,湖北武汉430060 [2]武汉大学人民医院耳鼻咽喉头颈外科Ⅰ科,湖北武汉430060

出　　处：《现代肿瘤医学》2015年第13期1931-1934,共4页Journal of Modern Oncology

基　　金：湖北省自然科学基金项目(编号:2014CFB420)

摘　　要：microRNA是一类非蛋白编码的微小RNA分子,在人类多种生理和病理过程中起着重要的调节作用。越来越多的证据表明,miRNA和食管癌关系十分密切。本文就miRNA在食管癌中的表达、对食管癌生物学特性的影响和对食管癌治疗、预后的价值及研究进展等方面作一综述。microRNA is a grouP of non-Protein coding small RNA molecules. It Plays imPortant regulatory roles in variety of Physiological and Pathological Processes in human being. More and more evidences indicated that,the rela-tionshiP between miRNA and esoPhageal cancer was inseParable. In this article,miRNA exPression in esoPhageal cancer,the imPact on the biological characteristics of esoPhageal cancer,treatment,Prognosis value and advance for e-soPhageal cancer were reviewed.

关 键 词：microRNA/miRNA/miR 食管癌 进展 

分 类 号：R735.1[医药卫生—肿瘤]