Synthesis, spectral, optical and anti-inflammatory activity of complexes derived from 2-aminobenzohydrazide with some rare earths  

作　　者：Nasser Mohammed Hosny El Sayed A.El Morsy Yousery E.Sherif 

机构地区：[1]Chemistry Department, Faculty of Science, Port-Said University [2]Clinical Pharmacology Department, Faculty of Medicine, Mansoura University [3]Pharmacology and Therapeutics Department, Qassim College of Medicine, Qassim University [4]Department of Chemistry, Faculty of Science and Arts, Taibah University

出　　处：《Journal of Rare Earths》2015年第7期758-764,共7页稀土学报（英文版）

摘　　要：Three new metal complexes derived from Er（Ⅲ）, Dy（Ⅲ） and Zr（Ⅳ） with 2-aminobenzohydrazide （ABH） were synthesized and characterized by elemental analyses, IR, ^1H-NMR, ES-MS and transmission electron microscopy （TEM）. The morphology and the particle size were determined by TEM. The results showed that the ligand acted as neutral bi-dentate coordinating to the metal ions through the carbonyl oxygen and amidic amino nitrogen. The aromatic amine group remained inert towards coordination. The optical band gap was measured and found to be 3.3, 3.5 and 4.3 eV for Er（Ⅲ）, Dy（Ⅲ） and Zr（Ⅳ）, respectively. The optical band gap values indicated a semi-conducting nature of the investigated complexes. The anti-inflammatory and analgesic activities of the tested compounds were determined and compared with standard meloxicam.Three new metal complexes derived from Er（Ⅲ）, Dy（Ⅲ） and Zr（Ⅳ） with 2-aminobenzohydrazide （ABH） were synthesized and characterized by elemental analyses, IR, ^1H-NMR, ES-MS and transmission electron microscopy （TEM）. The morphology and the particle size were determined by TEM. The results showed that the ligand acted as neutral bi-dentate coordinating to the metal ions through the carbonyl oxygen and amidic amino nitrogen. The aromatic amine group remained inert towards coordination. The optical band gap was measured and found to be 3.3, 3.5 and 4.3 eV for Er（Ⅲ）, Dy（Ⅲ） and Zr（Ⅳ）, respectively. The optical band gap values indicated a semi-conducting nature of the investigated complexes. The anti-inflammatory and analgesic activities of the tested compounds were determined and compared with standard meloxicam.

关 键 词：Er（Ⅲ） Dy（Ⅲ） Zr（Ⅳ） metal complexes optical band gap rare earths 

分 类 号：R914.5[医药卫生—药物化学] O641.4[医药卫生—药学]