奥曲肽联合前列地尔治疗急性胰腺炎临床疗效观察  

An Observation on Clinical Effect of Octreotide in Combination with Alprostadil on Octreotide

作　　者：何云天[1] 

机构地区：[1]化州市人民医院,化州525100

出　　处：《数理医药学杂志》2015年第7期1032-1033,共2页Journal of Mathematical Medicine

摘　　要：目的：研究分析急性胰腺炎应用奥曲肽联合前列地尔的治疗效果，丰富临床治疗经验。方法：选择2011年3月～2014年3月在某院确诊收治的110例急性胰腺炎患者，将其随机分为两组，各55例，对照组选用奥曲肽治疗，观察组给予奥曲肽联合前列地尔治疗。对比分析两组患者的临床治疗效果。结果：经治疗，患者的临床症状均明显改善，观察组患者的治疗总有效率为96．4％，显著优于对照组的81．8％，差异显著（P〈0．05）；观察组中有2例患儿治疗期间出现不良反应，不良反应率为2．5％，对照组中7例不良反应，不良反应率为10％，差异显著（P〈0．05）。结论：急性胰腺炎应用奥曲肽联合前列地尔治疗效果确切、安全可靠，值得临床大力推广。Objective：To study and analyze the effect of octreotide plus alprostadil on acute pancreatitis and to richen clinical experience. Methods：Select 110 cases of patients who were received in our hospital dur- ing the period from March 2011 to 2014 March and were diagnosed with acute pancreatitis ,randomly divide them into 2 groups, 55 cases for each group. Treat the control group with octreotide while the observation group with octreotide plus alprostadil. Compare the clinical effect in both group. Results：After treatment, pa- tients clinical symptoms had been improved, in observation group, the overall effective rate was 96. 4G, which was obviously better than than of the control group（81.8%） ,the difference was obvious（P〈0. 05） ;2 patients showed adverse reaction in observation group during treatment, the adverse reaction rate was 2.5 %, while in control group,7 patients had adverse reaction,the adverse reaction rate was 10% ,the difference was significant（P〈0.05）. Conclusion：It is effective safe and reliable to treat acute pancreatitis with octreotide in combination with alprostadil,it deserves vigorously clinical promotion.

关 键 词：奥曲肽 前列地尔 急性胰腺炎 疗效观察 

分 类 号：R576[医药卫生—消化系统]