全遮盖法治疗年长儿童屈光参差性弱视的疗效观察  

Effectiveness of full-time occlusion therapy for old children with anisometropic amblyopia

作　　者：林媚[1] 张至菲[2] 林燕婷[1] 

机构地区：[1]广东省江门市妇幼保健院眼科,529000 [2]美国密歇根韦恩州立大学医学院解剖与细胞生物系,48201

出　　处：《中华眼科医学杂志（电子版）》2015年第3期14-19,共6页Chinese Journal of Ophthalmologic Medicine(Electronic Edition)

摘　　要：目的：总结、评估全遮盖法治疗年长儿童屈光参差性弱视的疗效。方法收集2009年1月至2012年12月广东省江门市妇幼保健院眼科56例（56只眼）屈光参差性弱视患者的临床资料，患者均在10～16岁。所有患者经眼科常规检查和散瞳验光后确诊，并给予有视觉意义的屈光矫正治疗，全天连续遮盖非弱视眼。同时配合光栅及精细作业，每个月复查1次，随访2～4年。治疗前、后患者的视力以均数±标准差（ x±s）的形式表示，并采用配对t检验的方法进行比较。不同年龄、不同弱视程度及不同注视性质的患者治疗后6、12个月视力提高的幅度以均数±标准差（ x±s ）的形式表示，并采用独立样本 t 检验的方法进行组间比较，采用配对t 检验的方法进行组内比较。结果治疗后3个月弱视眼矫正视力提高1行及以上者50例（50只眼），占87.50％；提高2行及以上者31例（31只眼），占55.36％。治疗后6个月弱视眼矫正视力提高1行及以上者55例（55只眼），占98.21％；提高2行及以上者44例（44只眼），占78.57％。治疗后12个月弱视眼矫正视力提高1行及以上者56例（56只眼），占100.00％；提高2行及以上者48例（48只眼），占85.71％。治疗前患者弱视眼的平均矫正视力为（0.22±0.18），治疗后6个月患者弱视眼的平均矫正视力为（0.64±0.21），平均提高4.2行；治疗后12个月患者弱视眼的平均矫正视力为（0.66±0.23），平均提高视力4.4行，治疗后6、12个月患者弱视眼的平均矫正视力较治疗前明显提高，差异有统计学意义（t＝11.09，11.87；P＜0.05）。10～13岁组患者治疗后6个月视力提高幅度为（0.53±0.23），治疗后12个月视力提高幅度为（0.56±0.20）；14～16岁组患者治疗后6个月视力提高幅度为（0.31±0.18），治疗后12个月视力提高幅度为（0.56±0.20），治疗后6、12个月两组患者视力提高幅�Objec tive To evaluate the effectiveness of full-time patching or occlusion in treating anisometropic amblyopia in older children .Methods A total of 56 children （56 eyes） aged 10-16 years who presented to the Department of Ophthalmology , Jiangmen Maternal and Children′s Health Hospital with anisometropic amblyopia between January , 2009 and December , 2012 were enrolled in this study .After diagnosis of anisometropic amblyopia through routine ophthalmologic examinations pupil dilated optometry ,all patients underwent refraction correction and continuous full-time patching .After treatment , patients were followed up for 24 to 48 months during which monthly assessments were performed .Changes in visual acuity before and after treatment were analyzed .Results At three months after treatment , the corrected visual acuity of 50 patients （50 eyes） was improved 1 line or more with an overall effectiveness rate of 87.50%, and that of 31 patients （31 eyes） was improved 2 lines or more with an overall effectiveness rate of 55.36%. At 6 months after treatment ,the corrected visual acuity of 55 patients （55 eyes） was improved 1 line or more with an overall effectiveness rate of 98.21%, and that of 44 patients （44 eyes） was improved 2 lines ore more with an average overall effectiveness rate of 78.57%.At 12 months after treatment ,the corrected visual acuity of 56 patients （56 eyes） was improved 1 line ore more with an overall effectiveness rate of 100%,and that of 48 patients （48 eyes） was improved 2 lines or more with an overall effectiveness rate of 85.71%. Before treatment,the average corrected visual acuity of patients′amblyopia was （0.22±0.18）,while at 6 months after treatment , the average corrected visual acuity reached （ 0.64 ±0.21 ） with an average improvement of 4.2 lines.At 12 months after treatment, the average corrected visual acuity reached （0.66± 0.23） with an average improvement of visual acuity of 4.4 lines.At 6 and 12 months after treatment,the average corre

关 键 词：弱视 屈光参差 年长儿童 遮盖疗法 

分 类 号：R777.44[医药卫生—眼科]