吡啶催化L-谷氨酸消旋机理的探讨  

Exploration of L-glutamic Acid Racemic Mechanism Under the Catalysis of Pyridine

作　　者：王杰[1] 杨志洲[1] 姚金水[1] 

机构地区：[1]齐鲁工业大学材料科学与工程学院,山东济南250353

出　　处：《齐鲁工业大学学报》2015年第2期15-17,共3页Journal of Qilu University of Technology

基　　金：山东省自然科学基金项目(ZR2012EMZ003)

摘　　要：以L-谷氨酸和邻苯二甲酸酐为反应原料,吡啶为催化剂,所得的产物酰亚胺酸会出现外消旋化反应。通过对反应过程中旋光度的跟踪测试与分析,发现吡啶在起催化作用的同时还使反应体系的旋光度呈直线减弱,在此结果的基础上,再结合谷氨酸的分子结构特点,分析探讨了该反应体系的消旋机理。Racemic phenomenon of imide acid product will appear, when the condensation reaction of L-glutamic acid and phthalic anhydride is under catalysis of pyridine. By tracking and analysing, optical rotation in process of the reaction was found in a straight line decreasing. On the basis of the result, and combining with the molecular structure of L-glutamic acid, racemic mechanism of the reaction system was explored.

关 键 词：氨基酸 吡啶 外消旋 

分 类 号：O629.711[理学—有机化学]