皂苷对中枢神经系统疾病作用的研究进展  

Research Progress on Actions of Saponin for Central Nervous System Diseases

作　　者：侯梦洁 杨芸[1] 郑微微[1] 郑贵娟 黄嫒[1] 

机构地区：[1]嘉兴学院医学院,浙江嘉兴314001

出　　处：《今日健康》2015年第5期396-396,392,共2页

摘　　要：三七、人参、柴胡等临床常用中草药中主要有效成分都含有皂苷，已有研究表明其对机体多个系统均有不同程度的保护作用。由于以脑梗死、脑肿瘤、帕金森病等为代表的中枢神经系统疾病发病率和致残率较高，近年来国内外学者对皂苷在中枢神经疾病作用的研究正逐渐深入。本文综述了近年来各种皂苷对中枢神经系统疾病作用的研究进展。Saponin are natural glycosides of steroid or triterpene which widely distributed in clinical commonly used traditional Chinese herbals such as panax notoginseng, ginseng, radix bupleuri, etc. It is well established that saponins have protective effect on central nervous system, cardiovascular system and immune system. Patients suffering from the central nervous system diseases such as cerebral infraction, brain tumors and Parkinson＇s disease a high risk of morbidity and mortality. In recent years alone, there have been multiple advances in saponins on the research of the central nervous system diseases. This review will summarize the current advances concerning effects of different kinds of saponins on the central nervous system diseases.

关 键 词：皂苷 中枢神经系统疾病 脑血管疾病 癫痫 脑肿瘤 

分 类 号：R741[医药卫生—神经病学与精神病学]