宁夏某院不同年龄大肠息肉检出率及临床特征分析  

Detective rate and clinical characteristics of colorectal polyps at different ages

作　　者：武婧[1] 杨婧[1] 姚宇平 王超[1] 刘爱琴[1] 李倩倩[1] 翟惠虹[2] 

机构地区：[1]宁夏医科大学临床学院,银川750004 [2]宁夏医科大学总医院消化内科,银川750004

出　　处：《重庆医学》2015年第20期2737-2739,2742,共4页Chongqing medicine

基　　金：国家自然科学基金资助项目(81272686)

摘　　要：目的探讨宁夏医科大学总医院不同年龄组大肠息肉特点，为临床诊治提供客观依据。方法收集2002～2012年该院收治的经内镜及病理证实的大肠息肉患者837例，按患者年龄不同分为青年组（〈45岁）、中年组（45～59岁）、老年组（≥60岁），回顾性分析各组检出率、性别结构、临床表现、内镜特征、病理类型。结果各组检出率均呈逐年上升趋势且老年组高于青、中年组，发病年龄向年轻化发展，差异有统计学意义（P〈0．05）；青、中年组男性大肠息肉检出率明显高于女性，老年组性别构成差异无统计学意义（P〉0．05），青、中组男性检出率高于老年组男性，老年组女性检出率高于青、中年组女性，差异有统计学意义（P〈0．05）；青年组临床表现以无症状为主，中、老年组以大便性质改变为主；老年组大于或等于1cm、无蒂、多发息肉的构成比显著高于青、中年组，差异有统计学意义（P〈0．05）；3组均非腺瘤性息肉多于腺瘤性息肉，青、中年组非腺瘤性息肉构成比高于老年组，老年组腺瘤性息肉构成比、癌变率均高于青、中年组，差异有统计学意义（P〈0．05）。结论老年人患大肠息肉、发生癌变风险均高于青、中年，近年大肠息肉的发病有年轻化趋势，临床上应根据不同年龄组大肠息肉的特点制订筛查策略。Objective To compare the clinical and pathological characteristics of colorectal polyps at different ages in Ningx- ia. Methods 837 cases of colorectal polyps confirmed by the electronic colonoscopy who were treated at our hospital from January 2002 to January 2012 were enrolled and divided into three group：young group（age〈45 years）,middle aged group（45-59 years old） and elderly group （age≥60 years）. Analyzed and compared among three group in terms of the detective rate, gender composition, clinical,endoscopic and pathological types of colorectal polyps. Results The rate of patient admission increased year by year and the age of onset to incline to the young （P〈0.05）. Detectable rate in male higher than female in young and middle aged group,the pro- portion of male in young and middle aged group were higher, female in elderly group was significantly higher than others （P〈 0.05）. Asymptomatic was the main clinical manifestations in young group while change of stool customs in elderly group. The com- position of ≥ 1 cm, sessile, multiple polyps in elderly group are significantly higher than that in young group （P〈0.05）. No adeno- mas was the most common pathological type in three groups and higher in young and middle aged group,the composition of adeno- mas and the rate of malignancy in the elderly group was higher （P〈0.05）. Conclusion elder people suffer higher risk of colorectal polyps than young and middle aged people, and people who got colorectal polyps is becoming younger in recent years. We should choose corresponding endoscopic screening, diagnosis and treatment according to different characteristics of colorectal polyps for different age patients.

关 键 词：息肉 结肠镜检查 腺瘤 年龄 

分 类 号：R735.34[医药卫生—肿瘤]