GnRH 脉冲治疗非肥胖多囊卵巢综合征患者的不孕症  

Management of infertility in patients with non-obese polycystic ovary syndrome by micro-pulse infusion of GnRH

作　　者：贾慧英[1] 孙首悦[1] 王卫庆[2,3,4] 宁光[2,3,4] 

机构地区：[1]上海交通大学医学院附属瑞金医院北院内分泌科,201801 [2]上海交通大学医学院附属瑞金医院内分泌代谢病科,200025 [3]上海市内分泌代谢病临床医学中心 [4]上海市内分泌代谢病研究所

出　　处：《中华内分泌代谢杂志》2015年第6期528-529,共2页Chinese Journal of Endocrinology and Metabolism

基　　金：上海市卫生和计划生育委员会科研课题（201440528）

摘　　要：采用皮下脉冲输注促性腺激素释放激素（GnRH）治疗非肥胖 PCOS 不孕症患者。其中,1例32岁患者经治疗后,月经规律来潮,自然受孕并产下健康男婴。提示 GnRH 脉冲治疗可诱导非肥胖 PCOS不孕症患者自发排卵、自然受孕。[Summary] Patients with infertility and non-obese polycystic ovary syndrome （ PCOS） were treated with continuous subcutaneous pulse infusion of GnRH. After the treatment, a 32-year old female had regular menstrual cramps. Dominant follicle occurred after 2 months of treatment. The patient was pregnant and now has a healthy baby boy. It shows that the pulse infusion of GnRH could induce spontaneous ovulation and natural fertilization of the patients with non-obese PCOS.

关 键 词：垂体激素泵 GNRH 脉冲治疗 非肥胖 PCOS 妊娠 

分 类 号：R711.6[医药卫生—妇产科学]