硬化剂与组织粘合剂联合注射治疗活动性食管胃静脉曲张大出血  

The combined endoscopic injection with tissue adhesive and sclerosant for active hemorrhage of gastroesophageal varices

作　　者：申少华[1] 刘迎娣[2] 高伟[1] 柴国君[1] 孙国辉[1] 毛永平[1] 孙刚[1] 杨竞[1] 孙潇[1] 李萌[1] 

机构地区：[1]解放军总医院消化内科,北京100853 [2]解放军总医院海南分院消化内科

出　　处：《胃肠病学和肝病学杂志》2015年第6期710-713,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨硬化剂与组织粘合剂联合注射治疗活动性食管胃静脉曲张大出血的急诊疗效,总结内镜下联合注射治疗的临床经验。方法回顾分析5例食管胃静脉曲张活动性大出血患者的急诊内镜下硬化剂联合组织粘合剂注射治疗的临床特点,对静脉曲张内镜下表现、联合治疗时机、治疗方法及疗效进行分析。结果内镜下经硬化剂与组织粘合剂联合注射治疗后均达到即刻止血效果,止血成功率100%。随访6~24个月,其中1例经再次治疗后随访至24个月未见出血;其余4例随访无再出血发生。结论硬化剂与组织粘合剂联合注射治疗活动性食管胃静脉曲张大出血是一种安全、有效的方法,其近期及远期疗效可靠,值得临床推广。Objective To evaluate the effect of combined endoscopic injection with tissue adhesive and sclerosant （EITS） for gastroesophageal variceal active hemorrhage （GEVAH）. Methods Five patients with GEVAH were con- ducted EITS. Their clinical characteristics, especially endoscopic features of varices, the opportunity of the treatment, the efficacy and follow-up were analyzed. Results For the patients treated with EITS, the hemostasis rate was 100% and there was no significant complication. Five patients were successfully followed up for 6 months, with 1 patient reoc- curring hematemesis. During the 24-month follow-up, this patient didn＇ t have rebleeding after further treatment. No re- bleeding was found in the other 3 patients with 24-month follow-up and 1 patient with 6-month follow-up. Conclusion EITS for GEVAH is a safe and effective method. The short-term and long-term therapeutic effect is reliable, deserving clinical expansion.

关 键 词：硬化剂 组织粘合剂 食管胃静脉曲张 出血 

分 类 号：R57[医药卫生—消化系统]