胃神经内分泌肿瘤的诊断和治疗  

Diagnosis and treatment for gastric neuroendocrine tumors

作　　者：刘丹[1,2,3,4] 沈琳[1,2,3,4] 陆明[1,2,3,4] 

机构地区：[1]北京大学临床肿瘤学院 [2]北京肿瘤医院 [3]北京市肿瘤防治研究所消化道肿瘤多学科协作组,北京100142 [4]恶性肿瘤发病机制及转化研究教育部重点实验室,100142

出　　处：《临床肿瘤学杂志》2015年第6期549-554,共6页Chinese Clinical Oncology

摘　　要：胃神经内分泌肿瘤(G-NETs)是指来源于胃上皮及类肠嗜铬(ECL)细胞等神经内分泌细胞相关的肿瘤,占胃原发肿瘤一小部分,故长期以来对其认识局限,诊疗缺乏统一标准。但近年来G-NETs发病率较前明显升高,对其认识逐渐加深,临床根据G-NETs分化程度、与高胃泌素血症相关与否分为4个亚型,并针对不同亚型进行治疗。本文就近年来有关GNETs流行病学、临床表现、诊断标准、治疗方法等最新进展做一综述,以期为G-NETs的诊疗提供参考。Gastric neuroendocrine tumors（GNETs） arise in enterochromaffinlike（ECL） cells, which only account for a small part of gastric tumors. People have been less focused on them, so that the diagnosis and treatment of GNETs are lack of acknowledged guidelines. However, with the increasing incidence, there is more deeply acknowledge in this field. In clinical, GNETs are compromised of 4 subtypes according to differentiation and the relationship with hypergastrinemia. In the current review, we summarize the pathology, clinical characteristics, which aimed at treatment of it.

关 键 词：胃神经内分泌肿瘤 高胃泌素血症 萎缩性胃炎 卓-艾综合征 类癌综合征 

分 类 号：R735.2[医药卫生—肿瘤]