泮托拉唑治疗消化性溃疡合并出血疗效分析  

Analysis of curative effect by pantoprazole in the treatment of peptic ulcer complicated with hemorrhage

作　　者：黎美丽 

机构地区：[1]恩平市人民医院,529400

出　　处：《中国实用医药》2015年第18期53-54,共2页China Practical Medicine

摘　　要：目的探讨泮托拉唑治疗消化性溃疡合并出血的临床效果。方法 100例消化性溃疡合并出血患者,随机分为观察组和对照组,各50例。两组均给予常规治疗,对照组患者给予奥美拉唑治疗,观察组患者给予泮托拉唑治疗。评定两组治疗效果,观察不良反应发生情况。结果观察组治疗后的临床效果总有效率为96.0%,对照组治疗后的总有效率为78.0%,观察组总有效率高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率(8.0%)低于对照组(32.0%),差异有统计学意义(P<0.05)。结论泮托拉唑治疗消化性溃疡合并出血疗效显著,用药安全,值得借鉴。Objective To investigate the clinical effect of pantoprazole in the treatment of peptic ulcer complicated with hemorrhage. Methods A total of 60 peptic ulcer complicated with hemorrhage patients were randomly divided into observation group and control group, and each group received 30 cases. The observation group received pantoprazole for treatment, and the control group received omeprazole. Curative effects and adverse reactions were compared in the two groups. Results The observation group had total effective rate as 93.3%, and that of the control group was 90.0%. Their difference had no statistical significance （P＆gt;0.05）. The observation group had lower incidence of adverse reactions as 6.7% than 30.0% of the control group, and their difference had statistical significance （P＆lt;0.05）. Conclusion Pantoprazole provides precise effect with few adverse reactions in treating peptic ulcer complicated with hemorrhage, and it is worthy of referring.

关 键 词：消化性溃疡 出血 泮托拉唑 奥美拉唑 

分 类 号：R573.1[医药卫生—消化系统]