Keratograph 5M眼表综合分析仪观察小梁切除术后泪膜的早期变化  

Observation of the early tear film changes after trabeculectomy with Keratograph 5M

作　　者：赖钟祺 李维娜[1] 李惠娜[1] 

机构地区：[1]解放军第180医院眼科,中国福建省泉州市362000

出　　处：《国际眼科杂志》2015年第7期1282-1284,共3页International Eye Science

摘　　要：目的:运用Keratograph 5M眼表综合分析仪观察小梁切除术后泪膜的早期变化。方法:收集青光眼患者41例46眼,分别于小梁切除术前1d,术后1d;1wk;1mo行第一次泪膜破裂时间(first tear break up time,FTBUT)、平均泪膜破裂时间(average tear break up time,ATBUT)、非侵入式泪河高度(non-invasive tear meniscus height,NITMH)、脂质层厚度分级及睑板腺完整度评分检查。结果:与术前1d相比,术后1d;1wk;1mo的FTBUT、ATBUT缩短(P<0.05),脂质层变薄(P<0.017)。术后1d的NITMH高于术前1d,而术后1wk和1mo的NITMH低于术前1d(P<0.05)。睑板腺完整度评分手术前后差异无统计学意义(P>0.05)。结论:Keratograph 5M眼表综合分析仪可以快速、精确地评估泪膜的功能。青光眼小梁切除术在术后短期内可对泪膜的稳定性及泪液的分泌量产生不良影响。AIM ： To observe the early tear film changes after trabeculectomy using Keratograph 5M.METHODS： Fourty-one patients（ 46 eyes） of glaucoma who underwent trabeculectomy were involved. First tear break up time（ FTBUT）, average tear break up time（ ATBUT）,non-invasive tear meniscus height（ NITMH）,lipid layer thickness and meibomian gland scores w ere m easured at 1d preoperatively and at 1d, 1w k, 1m o postoperatively.RESULTS： At 1d,1wk and 1mo postoperatively,FTBUT and ATBUT decreased greatly（ P〈0. 05）,as well as lipid layer thickness（ P〈0. 017）. NITM H at 1d postoperatively increased significantly, but at 1w k and 1m o postoperatively decreased greatly（ P〈0. 05）. There was no significantly difference in meibomian gland scores between preoperation and postoperation（ P〉0. 05）. CONCLUSION： Keratograph 5M could be used to evaluate tear film function rapidly and accurately.Trabeculectomy significantly alters tear film stability and tear secretion in the short term after operation.

关 键 词：Keratograph5M眼表综合分析仪 小梁切除术 泪膜 

分 类 号：R779.6[医药卫生—眼科]