27例原发灶不明的颈部转移癌的临床分析  

A clinical study of 27 cases of cervical metastatic carcinoma of unknown primary site

作　　者：李文静[1] 辛丁[2] 张庆丰[1] 

机构地区：[1]大连市中心医院耳鼻咽喉头颈外科,辽宁大连116033 [2]吉林大学第二医院耳鼻咽喉头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2015年第13期1187-1190,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:分析27例原发灶不明的颈部转移癌的临床特点以指导临床诊断及治疗。方法:回顾性分析27例原发灶不明的颈部转移癌患者的临床资料。采用Kaplan-Meier法和Log-rank检验进行生存分析,多因素分析采用Cox回归模型。结果:性别、年龄及肿物位置对患者的中位生存期无显著性影响。病理类型不同,患者生存时间不同,差异有统计学意义(P<0.05)。治疗方案对患者中位生存期有显著影响(P<0.05),是影响患者预后的独立因素(P<0.05)。结论:及早确定转移灶的病理类型、原发灶的位置可提高患者预后,针对不同的病理类型采取不同治疗方案可提高患者生存率,联合治疗可使患者的生存期延长。Objective：To analyze the clinical feature of cervical metastatic carcinoma of unknown primary site（CCUP）for guiding clinical diagnosis and treatment.Method：Twenty-seven cases of CCUP during May 2007 to September 2013 in department were analyzed retrospectively.Kaplan-Meier method and Log-rank test were used for survival analysis,multivariate analysis using the Cox regression model.Result：There is no significant influence among gender,age and the mass position on the median survival time.Median survival time of patients with different pathological types was statistically significant（P〈0.05）.Treatment affected the median surial significantly（P〈0.05）and also was the independent prognostic factors（P〈0.05）.Conclusion：The early establishment of pathological type and primary focal position can improve the prognosis.Taking treatment according to pathological types can increase the patient′s survival rate.Combined treatment can prolong the patient′s survival time.

关 键 词：颈部转移癌 原发灶 诊断 分类 治疗 

分 类 号：R739.91[医药卫生—肿瘤]