颈动脉狭窄患者血管成形和支架植入术后血流动力学的改变  

Changes of hemodynamic after carotid angioplasty and stenting in patients with carotid artery stenosis

作　　者：孙红刚[1] 居克举[2] 高社荣[1] 

机构地区：[1]新疆生产建设兵团第七师医院神经内科,奎屯833200 [2]南京医科大学附属淮安第一医院神经内1科

出　　处：《临床神经病学杂志》2015年第3期229-231,共3页Journal of Clinical Neurology

基　　金：新疆生产建设兵团科技计划项目(2008ZJ18)

摘　　要：目的探讨颈动脉狭窄患者血管成形和支架植入术(CAS)后血流动力学的改变。方法给31例颈动脉狭窄患者行CAS。在术前、术后第1 d、3个月及1年时进行颈动脉彩色多普勒血流显像(CDFI)检查。比较手术前后颈动脉狭窄段的血管内径、峰值流速(PSV)和舒张末期流速(EDV)。结果与术前比较,患者术后各时间点颈动脉的血管内径明显增大,PSV和EDV明显降低(均P<0.01)。与术后第1 d比较,术后3个月的颈动脉CDFI各项指标的差异无统计学意义;与术后第1 d比较,术后1年的颈动脉血管内径缩小(P<0.05),PSV和EDV的差异无统计学意义。结论 CAS术后颈动脉狭窄得到缓解,血流动力学指标显著改善。术后1年时部分患者出现支架处血管再狭窄,但血流动力学无明显改变。Objective To explore the changes of hemodynamic after carotid angioplasty and stenting （ CAS） in patients with carotid artery stenosis .Methods Thirty-one carotid artery stenosis patients were treated with CAS , and were examined by color Doppler flow imaging （ CDFI） before operation and 1 d,3 months,one year after operation . Compared the carotid artery diameter , peak flow velocity （PSV） and end-diastolic velocity （EDV） before and after the operation.Results Compared with before operation , carotid artery diameter were significantly increased ,PSV, EDV were significantly decreased at each time point after operation （ all P〈0.01 ） .Compared with 1 d after operation, there was no statistical difference on the CDFI results of carotid artery in 3 months after operation;compared with 1 d after operation the carotid artery diameter was significanty decreased in one year after operation （ P〈0.05 ） , there was no statistical difference in PSV and EDV .Conclusions CAS can alleviate the carotid stenosis and improve the indicator of hemodynamics significantly .Vascular restenosis is found in some patients one year after operation , but there was no statistical difference in the indicator of hemodynamic .

关 键 词：颈动脉狭窄 颈动脉血管成形和支架植入术 彩色多普勒血流显像 

分 类 号：R743.3[医药卫生—神经病学与精神病学]