人体慢性低剂量农药暴露生物学监测研究进展  

Progress in researches on biological monitoring of chronic lowdose pesticide exposure

作　　者：邓媛英[1] 何微[1] 田静[1] 戴红梅[1] 赵玲玲[1] 

机构地区：[1]中南大学湘雅三医院,湖南长沙410013

出　　处：《中国公共卫生》2015年第7期900-903,共4页Chinese Journal of Public Health

基　　金：瑞士银行慈善基金(6102)

摘　　要：人体慢性低剂量农药暴露的生物学监测对于评估农药暴露对人体健康的影响有重要意义。生物学监测的标本来源除了目前使用广泛的尿液及血液标本,唾液、汗水、头发等也被用作农药暴露的生物学监测。监测的指标可以直接检测各种生物标本中的农药本身的化学物质及其代谢产物的含量,还可以通过间接指标如酶学、神经递质、DNA、蛋白质进行检测。选择合适的生物学监测方法可以为正确评估人体农药暴露提供有力的依据。本文对目前人体慢性低剂量农药暴露的生物学监测方法进行综述。The biological monitoring of chronic lowdose pesticide exposure has important implications for evaluating the effects of pesticide exposure on human health. The methods of biological monitoring were reviewed in the article.The biomonitoring samples include urine,blood,saliva,sweat and hair. The biomarkers include chemicals and metabolites of pesticides. Meanwhile,some indirect indexes such as enzyme,DNA,neurotransmitter,protein were also used as biomarkers of pesticide exposure. Appropriate method of biological monitoring can provide an efficient and cost-effective way to identify and quantify pesticide exposure.

关 键 词：农药暴露 慢性低剂量 生物学监测 

分 类 号：R155[医药卫生—营养与食品卫生学]