利用伤残调整寿命年评价新疆维吾尔自治区石河子市胃癌的疾病负担  

Using disability-adjusted life years to evaluate gastric cancer burden in Shihezi,Xinjiang Uygur Autonomous Region

作　　者：李慧[1] 李述刚[1] 张学飞[1] 闫贻忠 牛强[1] 徐上知[1] 刘园园[1] 

机构地区：[1]石河子大学医学院预防医学系

出　　处：《世界华人消化杂志》2015年第17期2791-2797,共7页World Chinese Journal of Digestology

基　　金：新疆兵团重大公共卫生专项基金资助项目;No.2100409;石河子大学国家级大学生创新创业训练计划基金资助项目;No.201310759069~~

摘　　要：目的:分析新疆维吾尔自治区石河子市胃癌的疾病负担,为新疆兵团地区胃癌的防治提供科学依据.方法:根据石河子市肿瘤登记处2010-01/2 0 1 1-1 2登记的恶性肿瘤发病及死亡资料,计算胃癌粗发病率、粗死亡率、标化发病率、标化死亡率、伤残调整寿命年(disability-adjusted life years,DALYs)、死亡损失寿命年(years of life lost with death,YLLs)、伤残损失寿命年(years lived with disability,YLDs)等指标,评价该地区胃癌的疾病负担.结果:2010-2011年石河子市胃癌粗发病率为19.84/10万,中标率为9.34/10万,世标率为12.83/10万;胃癌粗死亡率为9.66/10万,中标率为4.39/10万,世标率为6.22/10万.发病率和死亡率均为男性高于女性.同期该地区胃癌损失DALYs为988.11人年,YLLs为936.79人年,Y L D s为51.32人年.平均每千人DALYs为1.72人年,占全肿瘤DALYs的7.09%.YLLs和YLDs的每千人DALYs分别为1.63人年、0.09人年,分别占胃癌D A LY s的94.77%和5.23%.男性的DALYs、YLLs及每千人DALYs损失均明显高于女性,而女性的Y L D s高于男性.不同性别胃癌疾病负担从35岁开始随年龄增长而上升,在55-74岁年龄组间,胃癌疾病负担最重,超过75岁人群疾病负担呈下降趋势.结论:石河子市胃癌疾病负担主要由死亡损失引起,男性寿命影响大于女性,且对55岁以后人群危害严重,应对相应人群采取积极有效的干预措施.AIM：To analyze the burden of gastric cancer inShihezi,Xinjiang Uygur Autonomous Region to guide the prevention and control of gastric cancer in this area.METHODS：The data regarding incidence and mortality of gastric cancer from January 2010 to December 2011 were collected from Shihezi Cancer Registry.The indexes,including incidence,mortality,standardized mortality and mortality,disability-adjusted life years（DALYs）,years of life lost with death（YLLs）,and years lived with disability（YLDs）,were calculated to assess the local gastric cancer burden.RESULTS：The incidence of gastric cancer in Shihezi in 2010-2011 was 19.84/105,and the Chinese and world population standardized incidence was 9.34/105 and 12.83/105,respectively.The mortality was 9.66/105,and the Chinese and world population standardized incidence was 4.39/105 and 6.22/105,respectively.The incidence and mortality of gastric cancer in males were higher than those of females.During the period,DALYs,YLLs and YLDs in gastric cancer patients were 988.11,936.79 and 51.32 person years,respectively,with the respective value per 1000 population being 1.72,1.63 and 0.09.DALYs for gastric cancer patients accounted for 7.09% of the total DALYs for patients with malignant tumors,and YLLs and YLDs accounted for 94.77% and 5.23% of the total DALYs for gastric cancer patients,respectively.YLLs,DALYs and DALYs per 1000 population in male gastric cancer patients were higher than those of females,but YLDs in females were higher than those in males.The disease burden of gastric cancer in differentgenders began to increase from the 35-year group.In the 55-74 year group,disease burden in both males and females were the most serious.Disease burden in residents more than 75 years old gradually declined.CONCLUSION：The burden of gastric cancer in Shihezi is mainly caused by the death lost.The life span of males is impacted more seriously than that of females and people more than 55 years old suffer from gastric cancer much seriously than others.Consequently,effe

关 键 词：胃癌 疾病负担 伤残调整寿命年 死亡损失寿命年 伤残损失寿命年 

分 类 号：R735.2[医药卫生—肿瘤]