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机构地区:[1]徐州医学院研究生学院,江苏徐州221000 [2]徐州医学院公共卫生学院流行病学教研室,江苏徐州21000
出 处:《中国当代儿科杂志》2015年第7期721-725,共5页Chinese Journal of Contemporary Pediatrics
基 金:江苏高校哲学社会科学研究基金项目(2012SJB190015)
摘 要:目的:综合分析儿童注意缺陷多动障碍(ADHD)家庭危险因素,为今后防治工作提供依据。方法系统收集2000-2014年涉及中国儿童ADHD发病危险因素的病例对照文献,从中提取家庭因素有关数据;按照NOS标准对纳入文献进行质量评价;采用Stata 12.0软件对纳入文献进行Meta分析。结果最终纳入16篇文献,包括ADHD病例2167例,对照2148例。Meta分析显示,良好的教养方式(OR=0.32,95%CI:0.26-0.40)、核心家庭(OR=0.56,95%CI:0.41-0.76)、父亲文化程度高(OR=0.56,95%CI:0.41-0.76)、母亲文化程度高(OR=0.65,95%CI:0.47-0.89)、母亲性格外向(OR=0.33,95%CI:0.18-0.61)是儿童ADHD的保护因素;父母关系差(OR=1.90,95%CI:1.17-3.06)和ADHD家族史(OR=5.86,95%CI:3.67-9.35)是ADHD的危险因素。结论良好的教养方式、核心家庭类型、父母文化程度高以及母亲性格外向可降低儿童ADHD的发病风险,而父母关系差、ADHD家族史可增加ADHD患病的风险。[中国当代儿科杂志,2015,17(7):721-725]ObjectiveTo investigate the risk factors for attention deifcit hyperactivity disorder (ADHD) and to provide a basis for future prevention and treatment of this disease.MethodsFollowing a systematic search for case-control studies on the risk factors for ADHD in China between 2000 and 2014, relevant family risk factors were extracted accordingly. The quality of selected studies was evaluated according to the NOS scale. A Meta analysis on the selected studies was conducted using Stata 12.0 software.ResultsA total of 16 studies were selected, involving 2 167 children with ADHD and 2 148 normal controls. Results of Meta analysis showed that good parenting (OR=0.32, 95%CI: 0.26-0.40), nuclear family (OR=0.56, 95%CI: 0.41-0.76), high education level of father (OR=0.56, 95%CI: 0.41-0.76), high education level of mother (OR=0.65, 95%CI: 0.47-0.89), and extroversion of mother (OR=0.33, 95%CI: 0.18-0.61) are favorable factors for ADHD. Poor parental relationship (OR=1.90, 95%CI: 1.17-3.06) and family history of ADHD (OR=5.86, 95%CI: 3.67-9.35) are risk factors for ADHD.ConclusionsGood parenting, nuclear family, high education level of parents, and mother with extroversion are protective factors for ADHD, whereas poor parental relationship and family history of ADHD are associated with an increased risk for ADHD.
关 键 词:注意缺陷多动障碍 家庭 危险因素 META分析 儿童
分 类 号:R749.94[医药卫生—神经病学与精神病学]
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