腰椎单骨型骨纤维结构不良1例及文献复习  

Monostotic fibrous dysplasia of the lumbar spine: A case report and literature review

作　　者：张金康[1] 伍骥[1] 李松林[1] 黄蓉蓉[1] 

机构地区：[1]解放军空军总医院骨科,北京100142

出　　处：《现代肿瘤医学》2015年第15期2184-2187,共4页Journal of Modern Oncology

基　　金：国家自然科学基金青年科学基金项目(编号:81400859)

摘　　要：目的:结合文献复习,探讨脊柱单骨型骨纤维结构不良的治疗方法及预后。方法:报告1例经影像学、病理证实腰椎骨纤维结构不良的患者,行前路腰3椎体病灶及附件切除、L2-4间钛网置入脊柱前柱重建、植骨融合、MACS内固定术,并回顾相关文献。结果:术中切除部分腰3椎体及附件,重建脊柱稳定,病理检查结果提示:(L3椎体肿瘤)纤维结构不良,免疫组化结果示:CAM5.2(-)、CKpan(-)、EMA(-)。术后病人疼痛症状缓解,恢复良好。结论:脊柱单骨型纤维结构不良比较罕见,经前路病灶清除、植骨内固定可获得良好的治疗效果。Objective： To investigate the treatment and prognosis of anterior lumber corpectomy and fusion for monostotic fibrous dysplasia of the lumbar spine by literature review. Methods： A case of monostotic fibrous dysplasia of the lumbar spine was diagnosed by radiological and pathological tests and treated by lumber corpectomy,titanium mesh placement between L2-4,fusion with autologous bone graft and internal fixation with moldular anterior construct system（ MACS）. Results： We excised the lesion in L3 vertebral body and pedicle and reconstructed the spinal stability. Monostotic fibrous dysplasia was confirmed by pathological examination. The results of immunohistochemistry showed CAM5. 2（-）,CKpan（-） and EMA（-）. The pain was released and the patient recovered well after operation. Conclusion： Monostotic fibrous dysplasia of the lumbar spine was rare,and anterior lumber corpectomy,fusion with autologous bone graft and internal fixation with MACS could acquire good therapeutic effect.

关 键 词：纤维结构不良 单骨型 病理性骨折 椎间融合 

分 类 号：R738.1[医药卫生—肿瘤]