智能分光比色技术结合放大内镜与超声微探头判断早期食管癌浸润深度的对比研究  

Fuji intelligent chromoendoscopy combined with magnifying endoscopy vs miniature ultrasonic probe prediction for invasion depth of early esophageal carcinoma

作　　者：易楠[1] 周航[1] 刘邦伦[1] 王江红[1,2] 

机构地区：[1]重庆市肿瘤研究所内镜诊疗科,重庆400030 [2]广西医科大学研究生学院,南宁530021

出　　处：《第三军医大学学报》2015年第16期1657-1661,共5页Journal of Third Military Medical University

基　　金：重庆市卫计委医学科研面上项目(2013-2-199)~~

摘　　要：目的研究智能分光比色技术(fuji intelligent chromoendoscopy,FICE)判断早期食管癌浸润深度的诊断价值。方法 2011年1月至2014年5月重庆市肿瘤医院胃镜检查发现224例食管黏膜病变,分别用FICE结合放大内镜以及超声微探头(miniature ultrasonic probe,MPS)判断病灶性质及病变浸润深度,最终以病理结果作为诊断金标准进行对比分析。结果 FICE结合放大内镜在判断早期食管癌浸润深度方面准确率高于MPS(P<0.05),与术后病理结果达到中度一致(P<0.01);FICE结合放大内镜判断癌组织是否突破食管黏膜下层中1/3(sm2)有较高的灵敏度和特异度。结论 FICE技术操作简单、图像直观,结合放大内镜诊断食管疾病真实性较好,在判断早期食管癌浸润深度方面有较高的诊断价值。Objective To investigate the value prediction of the depth of invasion in early esophageal esophageal of Fuji intelligent chromoendoscopy （FICE） in the carcinoma. Methods Totally 224 patients with mucosa lesions admitted in Chongqing Cancer Hospital from January 2011 to May 2014 were enrolled in this study. They all underwent FICE combined with magnifying endoscopy and miniature ultrasonic probe（ MPS ） to detect the lesions and the depth of invasion. The obtained results were compared with histopathological results. Results The correct rate of FICE combined with magnifying endoscopy was significantly higher than MPS in evaluation of early esophageal cancer invasion depth （P 〈 0. 05 ）, and was consistent to the results of postoperative pathological examination （P 〈 0. 01 ）. FICE combined with magnifying endoscopy had high sensitivity and specificity in the judgement of whether cancer breakthrough in the middle of 1/3 of esophageal submucosa （sm2）. Conclusion FICE is simple, intuitionistic to display images, and of good visualization when combined with magnifying endoscopy. So it has a real good authenticity in diagnosis of the depth of invasion of esophageal diseases.

关 键 词：智能分光比色技术 食管肿瘤 腔内超声检查 内镜黏膜下剥离术 

分 类 号：R573[医药卫生—消化系统] R302[医药卫生—内科学]