胰腺炎住院患者合并严重皮肤感染的病原学分析及临床治疗  

Pathogenic analysis and clinical treatment of inpatients with pancreatitis and severe skin infection

作　　者：徐辉[1] 郑坚江[1] 多力坤[1] 多鲁坤[1] 

机构地区：[1]新疆维吾尔自治区人民医院胰腺外科,新疆乌鲁木齐830000

出　　处：《胃肠病学和肝病学杂志》2015年第7期872-874,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨胰腺炎住院患者合并严重皮肤感染的病原菌及其耐药性,找出敏感抗生素并及时联合激素应用,以提高临床治疗水平。方法随机选取2011年1月-2013年3月61例胰腺炎住院患者为研究对象,对其中伴有严重皮肤感染的39例患者进行病原菌和耐药性分析。结果共分离出病原菌52株,其中革兰阴性菌占全部病原菌的48.08%,革兰阳性菌占30.77%,真菌占21.15%。在革兰阴性菌中耐药性较低的抗菌药物有利福平、亚胺培南,均为0,而在革兰阳性菌中耐药性较低的抗生素为替考拉宁、万古霉素,均为0,真菌中耐药性较低的抗生素为5-氟胞嘧啶、两性霉素B,均为0。经一系列对症治疗后总有效率为66.67%,死亡率20.51%。结论胰腺炎住院患者合并严重皮肤感染病原菌较为均匀,选择敏感抗生素可提高临床疗效。Objective To investigate the pathogens of inpatient with pancreatitis and severe skin infections and its drug resistance,antibiotics and promptly identify the combined hormone sensitive applications to improve the level of clinical treatment. Methods Sixty-one inpatients with pancreatitis were randomly selected from Jan. 2011 to Mar.2013 for the study,of which 39 with severe skin infections with drug-resistant pathogens and analysis. Results The distribution of the pathogen compare 52 were isolated pathogens, including gram-negative bacteria accounted for48. 08% of all bacteria,gram-positive bacteria accounted for 30. 77%,fungi accounted for 21. 15%. In gram-negative bacteria resistant to antimicrobial drugs less rifampicin,imipenem,were 0,while in gram-positive bacteria resistant to antibiotics lower teicoplanin,vancomycin,were 0,a low resistance to fungal antibiotic is 5-fluorocytosine,amphotericin B,0. After a series of symptomatic total effective rate was 66. 67%,20. 51% mortality rate. Conclusion Inpatients with pancreatitis and severe skin infection pathogens more uniform,select sensitive antibiotics can improve clinical effects.

关 键 词：胰腺炎 严重皮肤感染 病原学 耐药性 

分 类 号：R735.35[医药卫生—肿瘤]