Sysmex XT-1800i血细胞分析仪白细胞分类报警系统(Q-Flag)的临床应用价值  

The value of clinical application of leukocyte classification alarm system(Q-Flag)for Sysmex XT-1800i blood cell analyzer

作　　者：韩冰 高阳 李康[2] 宋其生 于滨 

机构地区：[1]大连市结核病医院,辽宁大连116037 [2]深圳市龙岗中心医院中心实验室,广东深圳518116

出　　处：《国际检验医学杂志》2015年第14期2013-2014,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨Sysmex XT-1800i血细胞分析仪白细胞分类报警系统（Q-Flag）的临床应用价值。方法对Sysmex XT-1800i分析仪白细胞分类Q-Flag报警信息的标本394份和无异常报警信息的标本190份进行人工显微镜复检,观察全血细胞数量和形态学变化,并进行比较。结果 Sysmex XT-1800i分析仪对异常细胞报警的灵敏度为100.0%,特异性为62.3%,阳性预测值为70.8%和阴性预测值为100.0%。以人工显微镜复检为＂金标准＂,血细胞分析仪未出现Q-Flag报警信息时,人工显微镜复检未见异常细胞,符合率为100%;Sysmex XT-1800i分析仪在100 U≤Q-Flag〈200 U报警时,白细胞分类符合率为0%-75.0%;在200U≤Q-Flag≤300U报警时,白细胞分类符合率为66.7%-95.6%。结论 Sysmex XT-1800i分析仪白细胞分类报警系统（Q-Flag）灵敏度高,异常Q-Flag报警的标本必须人工显微镜复检,为临床提供准确可靠的诊断信息。Objective To study the value of clinical application of leukocyte classification alarm system（Q-Flag）for Sysmex XT-1800 iblood cell analyzer.Methods 394 blood samples with alarm system（Q-Flag）and 190 ones without abnormal alarm information detected by the Sysmex XT-1800 iblood cell analyzer were performed to observe the quantity and morphology of blood cells by manual differentiation,and the results were compared between them.Results The alarm system of Sysmex XT-1800 iblood cell analyzer in detecting cell morphologic abnormalities was 100.0%for sensitivity,62.3% for specificity,70.8% for positive predictive value and 100.0%for negative predictive value.Based on the ＂gold standard＂ of manual differentiation,no abnormal cells were observed in those blood samples without Q-Flag alarm information and the coincidence rate was 100%.The coincidence rate of leukocyte classification was from 0.0% to 75.0% for blood cell analyzer when the alarm system（Q-Flag）was between 100Uand200 U,and that was from 66.7%to 95.6% when the alarm system（Q-Flag）was between 200 Uand 300U.Conclusion The alarm system sensitivity of leukocyte classification alarm system（Q-Flag）is high for Sysmex XT-1800 iblood cell analyzer,and it is necessary to manually differentiate the samples with abnormal Q-Flag in order to provide accurate and reliable clinical diagnostic information.

关 键 词：SYSMEX XT-1800i血细胞分析仪 报警信息 复检 血细胞 

分 类 号：R446.11[医药卫生—诊断学]