两种术式治疗维族和汉族初发性翼状胬肉患者的疗效  

Curative effect of two kinds of operations for the treatment of primary pterygium between Uygur and Han patients

作　　者：王园园[1] 朱英[1] 刘雪清[1] 马平[1] 樱峰[1] 阿克来 

机构地区：[1]新疆医科大学第二附属医院眼科

出　　处：《国际眼科杂志》2015年第8期1466-1468,共3页International Eye Science

摘　　要：目的：探讨维、汉族用不同术式治疗初发性翼状胬肉的术后反应及复发率。方法：回顾性分析于新疆医科大学第二附属医院就诊且行手术治疗的翼状胬肉患者91例107眼,排除失访者,进行翼状胬肉单纯切除术者54眼（维吾尔族25眼,汉族29眼）;行翼状胬肉切除联合自体角膜缘干细胞移植术者45眼（维吾尔族20眼,汉族25眼）。术后观察患者角膜上皮细胞完整性恢复时间、异物感消失时间,并随访6-24mo,观察翼状胬肉的复发率及其并发症的发生。结果：行翼状胬肉单纯切除术患者中,维吾尔族患者复发11眼（44%）,汉族患者复发8眼（27.59%）;发生睑球粘连者中,维吾尔族患者0眼,汉族患者1眼;联合角膜缘干细胞移植术患者中,维吾尔族患者复发3眼（15%）,汉族患者复发1眼（4%）;汉族未见睑球粘连者,维吾尔族1眼发生睑球粘连。维吾尔族患者及汉族患者分别在翼状胬肉单纯切除术及及翼状胬肉切除联合角膜缘干细胞移植术两种术式后,随访6-24mo,对翼状胬肉的复发率进行χ^2检验,两者比较均有统计学意义（χ^2维=4.36,χ^2汉=3.81,P〈0.05）。维吾尔族及汉族患者翼状胬肉单纯切除术治疗翼状胬肉复发率,差异无统计学意义（χ^2=1.59,P〉0.05）。维吾尔族及汉族患者翼状胬肉切除术联合角膜缘干细胞移植术治疗翼状胬肉复发率,差异无统计学意义（χ^2=2.14,P〉0.05）。结论：无论是对于维吾尔族还是汉族来说,翼状胬肉切除术联合角膜缘干细胞移植术较单纯切除翼状胬肉能有效降低翼状胬肉复发率,故较适合当地居民。AIM：To evaluate postoperative reaction and the recurrence rate of two difference operation methods for the treatment of primary pterygium between Uygur and Han patientsMETHODS：A retrospective analysis was carried out in91 cases（107 eyes） with primary pterygium undergone surgical treatment in the Second Affiliated Hospital of Xinjiang Medical University.Excluded the patients who lost to follow,54 eyes（Uighur 25 eyes,Han 29 eyes）underwent pterygium simple resection,45 eyes（Uighur20 eyes,Han 25 eyes） received pterygium excision combined with limbal stem cell transplantation.Postoperative corneal epithelium integrity recovery time,foreign body sensation disappeared time,the occurrence of pterygium recurrence rate and complications were observed.The patients were followed up 6-24mo,RESULTS：In the patients undergone pterygium simple resection,11 eyes（44%） of Uighur and 8 eyes（27.59%）of Han recurred.0 eye of Uighur and 1 eye of Han patient occurred symblepharon.In the patients received pterygium excision combined with limbal stem cell transplantation,3 eyes（15%） of Uighur and 1 eye（4%）of Han recurred.No symblepharon occurred in Han patients,and 1 eye of Uighur occurred symblepharon.During 6 -24mo of follow-up,Chi-square test was used to compare the recurrence rate between two groups,and there was statistical significance（χ^2Uighur=4.36,χ^2Han=3.81;P〈0.05）.In two groups,there was no statistically significant difference on pterygium recurrence rate between Uighur and Han（χ^2simple=1.59,χ^2combine=2.14;P〉0.05）.CONCLUSION：Whether it is for Uighur or Han,pterygium excision combined with limbal stem cell transplantation has lower pterygium recurrence rate than pterygium simple excision,it is more appropriate to local residents.

关 键 词：维吾尔族 汉族 初发性翼状胬肉 角膜缘干细胞移植术 复发率 

分 类 号：R779.6[医药卫生—眼科]