脂肪肝常见中医证型与彩色多普勒超声形态学、血流动力学及生化指标的关系分析  

Relationship of Fatty Liver Common Syndrome Types and Color Doppler Ultrasound Morphology,Hemodynamics and Blood Biochemistry Analysis

作　　者：许莉华[1] 

机构地区：[1]浙江中医药大学附属第一医院超声科,浙江杭州310000

出　　处：《中华中医药学刊》2015年第8期2024-2026,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:探讨脂肪肝常见中医证型与彩色多普勒超声形态学、血流动力学及生化指标的关系。方法:选择2012年5月—2014年5月收治的脂肪肝患者120例,按照中医辨证分析分为肝气郁滞型63例、痰湿内阻型34例以及痰瘀阻络型23例,再选择同期健康对照50例作为对照组,比较不同程度脂肪肝患者中医证型的分布,不同证型门静脉内径、平均血流速度、肝静脉收缩期峰值血流速度以及血生化指标。结果:肝郁气滞型以轻度脂肪肝为主、痰湿内阻型以中度脂肪肝为主、痰瘀阻络型以重度脂肪肝为主,比较差异具有统计学意义(P<0.05);肝气郁滞型患者与对照组比较,门静脉内径以及平均血流速度均无统计学差异(P<0.05);而痰湿内阻型、痰瘀阻络型与对照组比较,门静脉内径显著增宽、平均血流速度显著降低(P<0.05);肝气郁滞型肝静脉收缩期峰值血流速度与对照组无显著性差异(P>0.05),而痰湿内阻型、痰瘀阻络型较对照组肝静脉收缩期峰值血流速度显著降低(P<0.05);三种中医证型TC、TG、ATL与对照组比较均显著升高(P<0.05),痰瘀阻络型TC、TG、ALT显著高于肝气郁滞型以及痰湿内阻型(P<0.05),痰湿内阻型显著TC、TG、ALT显著高于肝气郁滞型(P<0.05)。结论:脂肪肝患者不同中医证型与其彩色多普勒超声形态学、血流动力学以及生化指标具有着一定的相关性,通过彩色多普勒超声检查不同中医证型脂肪肝患者的表现,能够为患者病情的发展以及预后提供客观的指标,对于进一步认识脂肪肝中医分型具有着重要的临床意义。Objective： To investigate the relationship of the common TCM syndrome types of fatty liver and color Doppler ultrasound hemodynamics and morphology, biochemical index. Methods： 120 patients with fatty liver in May 2012 -May 2014 admitted to our hospital, according to the analysis of traditional Chinese medicine, were divided into 34 cases of liver qi stagnation type ,63 eases of phlegm dampness and 23 cases of phlegm and blood stasis type and at the same pe- riod 50 healthy controls were compared. The distribution of different degrees of fatty liver patients in traditional Chinese medicine syndrome types, different types of portal vein diameter, mean blood flow velocity of hepatic vein, peak systolic blood flow velocity and blood biochemical index were observed. Results： The liver and qi stagnation type with mild fatty liver, stagnation of phlegm dampness type with moderate fatty liver and phlegm and blood stasis type with severe fatty liver had significant difference （P 〈 O. 05 ）. Compared with liver qi stagnation type patients and the controls, portal vein diame- ter and the average blood flow velocity had no statistical difference （ P 〈 0.05 ） and when the stagnation of phlegm damp- ness type,phlegm and blood stasis type compared with the control group, the portal vein diameter was significantly wid- ened and the mean blood flow velocity was significantly decreased （ P 〈 0.05 ）. The liver qi stagnation type~ hepatic vein systolic peak flow velocity had no significant difference compared with those of the control group （P 〉 0.05 ） and when the phlegm dampness type and phlegm and blood stasis type compared with the control group, the hepatic vein systolic peak flow velocity （P 〈 0.05 ） decreased significantly. Three kinds of TCM syndrome types＇TC, TG and ATL significantly increased compared with＇ those of the control group （ P 〈 0.05 ） and phlegm and blood stasis type＇s TC ,TG and ALT were significantly higher than that of liver qi stagnation and phlegm dampness ty

关 键 词：脂肪肝 中医证型 彩色多普勒超声 

分 类 号：R575.5[医药卫生—消化系统]