振幅整合脑电图评分系统在早产儿脑损伤早期诊断的价值  

The Use of the Scoring System of Amplitude Integrated Electroencephalogram for Early Diagnosis of Brain Injury in Premature Infants

作　　者：王德胜[1] 赖丽芝[1] 蒋新华[1] 何康成 

机构地区：[1]暨南大学医学院附属东莞医院,广东东莞523900

出　　处：《中国医学创新》2015年第22期50-53,共4页Medical Innovation of China

基　　金：广东省科技基金项目(20130319C)

摘　　要：目的：研究振幅整合脑电图（a EEG）评分系统在早产儿临床脑损伤早期诊断的应用价值。方法：对50例胎龄27～36周脑损伤早产儿（脑损伤组）于生后48 h内行a EEG描记,利用a EEG评分系统分析背景波连续性、睡眠觉醒周期、下边界振幅及波谱带宽度,四参数分值相加得总分,用相应孕周早产儿总分平均值减去原始分得校正后总分,以消除不同胎龄所致差异,并与40例无脑损伤早产儿（对照组）作比较。校正后总分越高,提示a EEG异常程度越重。结果：脑损伤组a EEG校正后总分为（0.82±1.14）分,高于对照组（0.23±1.07）分,比较差异有统计学意义（P〈0.05）。结论：27～36周早产儿出生早期a EEG评分可反映脑功能的改变,对早产儿脑损伤具有预测作用。Objective： To assess the predictive value of the scoring system of amplitude integrated electroencephalogram （ aEEG ） in premature infants with brain injury. Method： 50 brain damage infants with 27-36 weeks gestational age were selected. 8-hour continuous aEEG recording was performed to each infants during the first 48 hours of life. The features of aEEG scoring system, including continuity, sleep-waking cycle, degree of voltage amplitude depression and bandwidth, were evaluated. All variables were summed to yield a total score. The total scores was correlated with gestational and posteonceptional ages, called adjusted total scores, and compared with those of 40 normal premature infants （ control group ） . Higher adjusted total scores suggest severer cerebral damage. Result： The adjusted total score was significantly higher in brain injury group （ 0.82± 1.14 ） points, than （ 0.23± 1.07 ） points in control group （ P〈0.05 ） . Conclusion： The scoring system in the initial aEEG is predictive for brain injury in premature infants with 27-36 weeks gestational age.

关 键 词：振幅整合脑电图 脑损伤 早产儿 

分 类 号：R742[医药卫生—神经病学与精神病学]